Literature DB >> 231450

Acetamide--a metabolite of metronidazole formed by the intestinal flora.

R L Koch, E J Chrystal, B B Beaulieu, P Goldman.   

Abstract

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Year:  1979        PMID： 231450     DOI： 10.1016/0006-2952(79)90407-6

Source DB:  PubMed          Journal:  Biochem Pharmacol        ISSN： 0006-2952            Impact factor:   5.858


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  17 in total

Review 1.  Drug-gut microbiota interactions: implications for neuropharmacology.

Authors:  Jacinta Walsh; Brendan T Griffin; Gerard Clarke; Niall P Hyland
Journal:  Br J Pharmacol       Date:  2018-06-28       Impact factor: 8.739

Review 2.  Gut microbiome interactions with drug metabolism, efficacy, and toxicity.

Authors:  Ian D Wilson; Jeremy K Nicholson
Journal:  Transl Res       Date:  2016-08-13       Impact factor: 7.012

3.  Metabolism of a 5-nitroimidazole in susceptible and resistant isogenic strains of Bacteroides fragilis.

Authors:  J P Carlier; N Sellier; M N Rager; G Reysset
Journal:  Antimicrob Agents Chemother       Date:  1997-07       Impact factor: 5.191

4.  5-(Hydroxyimino)-4-methoxy-2-(pivaloylimino)thiazolidine-3 -acetamide, a reduced nitroheterocyclic derivative with potent schistosomicidal properties.

Authors:  P J Islip; M V Bogunović-Batchelor
Journal:  Experientia       Date:  1985-10-15

5.  Relationship between metronidazole metabolism and bactericidal activity.

Authors:  E J Chrystal; R L Koch; M A McLafferty; P Goldman
Journal:  Antimicrob Agents Chemother       Date:  1980-10       Impact factor: 5.191

6.  Interaction of metronidazole with resistant and susceptible Bacteroides fragilis.

Authors:  M A McLafferty; R L Koch; P Goldman
Journal:  Antimicrob Agents Chemother       Date:  1982-01       Impact factor: 5.191

Review 7.  Individual variation in first-pass metabolism.

Authors:  Y K Tam
Journal:  Clin Pharmacokinet       Date:  1993-10       Impact factor: 6.447

8.  Metronidazole metabolism in cultures of Entamoeba histolytica and Trichomonas vaginalis.

Authors:  B B Beaulieu; M A McLafferty; R L Koch; P Goldman
Journal:  Antimicrob Agents Chemother       Date:  1981-09       Impact factor: 5.191

9.  Studies on the disposition of a 5-nitroimidazole in laboratory animals.

Authors:  A Barrow; S R Burford; T J Forrest; A J Hawkins; D A Rose; P M Stevens; C W Vose; C M Walls
Journal:  Eur J Drug Metab Pharmacokinet       Date:  1987 Apr-Jun       Impact factor: 2.441

10.  Gut Pharmacomicrobiomics: the tip of an iceberg of complex interactions between drugs and gut-associated microbes.

Authors:  Rama Saad; Mariam R Rizkallah; Ramy K Aziz
Journal:  Gut Pathog       Date:  2012-11-30       Impact factor: 4.181
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