J Krudewig 1 , U Baumann , H Bernuth von , M Borte , U Burkhard-Meier , G Dueckers , E Foerster-Waldl , K Franke , P Habermehl , M Hönig , W Kern , K Kösters , K Kugel , T Lehrnbecher , J Liese , R Marks , G A Müller , R Müller , D Nadal , H-H Peter , D Pfeiffer-Kascha , M Schneider , H Sitter , P Späth , V Wahn , T Welte , T Niehues Show Affiliations »
Abstract
BACKGROUND: Currently, management of antibody deficient patients differs significantly among caregivers. Evidence and consensus based (S3) guidelines for the treatment of primary antibody deficiencies were developed to improve the management of these patients. METHODS: Based on a thorough analysis of current evidence (systematic literature search in PubMed; deadline November 2011) 14 recommendations were finalized during a consensus meeting in Frankfurt in November 2011 using structured consensus methods (nominal group technique). Experts were nominated by their scientific societies/patient initiatives (Tab. 1). RESULTS: The guidelines focus on indication, practical issues and monitoring of immunoglobulin replacement therapy as well as on different routes of administration. Furthermore recommendations regarding supportive measures such as antiinfective therapy, vaccinations and physiotherapy are given. Combining literature evidence and experience of caregivers within this evidence and consensus based guidelines offers the chance to improve the quality of care for anti-body deficient patients. © Georg Thieme Verlag KG Stuttgart · New York.
BACKGROUND: Currently, management of antibody deficient patients differs significantly among caregivers. Evidence and consensus based (S3) guidelines for the treatment of primary antibody deficiencies were developed to improve the management of these patients . METHODS: Based on a thorough analysis of current evidence (systematic literature search in PubMed; deadline November 2011) 14 recommendations were finalized during a consensus meeting in Frankfurt in November 2011 using structured consensus methods (nominal group technique). Experts were nominated by their scientific societies/patient initiatives (Tab. 1). RESULTS: The guidelines focus on indication, practical issues and monitoring of immunoglobulin replacement therapy as well as on different routes of administration. Furthermore recommendations regarding supportive measures such as antiinfective therapy, vaccinations and physiotherapy are given. Combining literature evidence and experience of caregivers within this evidence and consensus based guidelines offers the chance to improve the quality of care for anti-body deficient patients . © Georg Thieme Verlag KG Stuttgart · New York.
Entities: Disease
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Year: 2012
PMID： 23143768 DOI： 10.1055/s-0032-1323837
Source DB: PubMed Journal: Klin Padiatr ISSN： 0300-8630 Impact factor: 1.349