Literature DB >> 23143366

Efficacy of different cleaning and disinfection methods against Clostridium difficile spores: importance of physical removal versus sporicidal inactivation.

William A Rutala1, Maria F Gergen, David J Weber.   

Abstract

We tested the effectiveness of disinfectants and wipe methods against Clostridium difficile spores. Wiping with nonsporicidal agents (physical removal) was effective in removing more than 2.9 log(10) C. difficile spores. Wiping with sporicidal agents eliminated more than 3.90 log(10) C. difficile spores (physical removal and/or inactivation). Spraying with a sporicide eliminated more than 3.44 log(10) C. difficile spores but would not remove debris.

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Year:  2012        PMID: 23143366     DOI: 10.1086/668434

Source DB:  PubMed          Journal:  Infect Control Hosp Epidemiol        ISSN: 0899-823X            Impact factor:   3.254


  11 in total

Review 1.  Dentists, antibiotics and Clostridium difficile-associated disease.

Authors:  N Beacher; M P Sweeney; J Bagg
Journal:  Br Dent J       Date:  2015-09-25       Impact factor: 1.626

2.  Activity of Hospital Disinfectants against Vegetative Cells and Spores of Clostridioides difficile Embedded in Biofilms.

Authors:  Tasnuva Rashid; Farnoosh Haghighi; Irtiza Hasan; Eugénie Bassères; M Jahangir Alam; Shreela V Sharma; Dejian Lai; Herbert L DuPont; Kevin W Garey
Journal:  Antimicrob Agents Chemother       Date:  2019-12-20       Impact factor: 5.191

Review 3.  Controlling hospital-acquired infection: focus on the role of the environment and new technologies for decontamination.

Authors:  Stephanie J Dancer
Journal:  Clin Microbiol Rev       Date:  2014-10       Impact factor: 26.132

Review 4.  Hospital Infection Control: Clostridioides difficile.

Authors:  Nicholas A Turner; Deverick J Anderson
Journal:  Clin Colon Rectal Surg       Date:  2020-02-25

5.  Editorial Commentary: looking to the future: vertical vs horizontal prevention of Clostridium difficile infections.

Authors:  L Clifford McDonald
Journal:  Clin Infect Dis       Date:  2013-07-23       Impact factor: 9.079

6.  Determinants of disinfectant use among nurses in U.S. healthcare facilities.

Authors:  Orianne Dumas; Aleta S Wiley; Paul K Henneberger; Frank E Speizer; Jan-Paul Zock; Raphaëlle Varraso; Nicole Le Moual; Krislyn M Boggs; Carlos A Camargo
Journal:  Am J Ind Med       Date:  2016-11-15       Impact factor: 2.214

Review 7.  Diversity and Evolution in the Genome of Clostridium difficile.

Authors:  Daniel R Knight; Briony Elliott; Barbara J Chang; Timothy T Perkins; Thomas V Riley
Journal:  Clin Microbiol Rev       Date:  2015-07       Impact factor: 26.132

Review 8.  A systematic review of chlorine-based surface disinfection efficacy to inform recommendations for low-resource outbreak settings.

Authors:  Karin Gallandat; Riley C Kolus; Timothy R Julian; Daniele S Lantagne
Journal:  Am J Infect Control       Date:  2020-05-19       Impact factor: 2.918

Review 9.  Disruption of the Gut Microbiome: Clostridium difficile Infection and the Threat of Antibiotic Resistance.

Authors:  Priscilla A Johanesen; Kate E Mackin; Melanie L Hutton; Milena M Awad; Sarah Larcombe; Jacob M Amy; Dena Lyras
Journal:  Genes (Basel)       Date:  2015-12-21       Impact factor: 4.096

10.  Surface area wiped, product type, and target strain impact bactericidal efficacy of ready-to-use disinfectant Towelettes.

Authors:  Alyssa M West; Carine A Nkemngong; Maxwell G Voorn; Tongyu Wu; Xiaobao Li; Peter J Teska; Haley F Oliver
Journal:  Antimicrob Resist Infect Control       Date:  2018-10-11       Impact factor: 4.887

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