Literature DB >> 23143354

Effective antimicrobial stewardship in a long-term care facility through an infectious disease consultation service: keeping a LID on antibiotic use.

Robin L P Jump1, Danielle M Olds, Nasim Seifi, Georgios Kypriotakis, Lucy A Jury, Emily P Peron, Amy A Hirsch, Paul E Drawz, Brook Watts, Robert A Bonomo, Curtis J Donskey.   

Abstract

DESIGN: We introduced a long-term care facility (LTCF) infectious disease (ID) consultation service (LID service) that provides on-site consultations to residents of a Veterans Affairs (VA) LTCF. We determined the impact of the LID service on antimicrobial use and Clostridium difficile infections at the LTCF.
SETTING: A 160-bed VA LTCF.
METHODS: Systemic antimicrobial use and positive C. difficile tests at the LTCF were compared for the 36 months before and the 18 months after the initiation of the ID consultation service through segmented regression analysis of an interrupted time series.
RESULTS: Relative to that in the preintervention period, total systemic antibiotic administration decreased by 30% (P<.001), with significant reductions in both oral (32%; P<.001) and intravenous (25%; P=.008) agents. The greatest reductions were seen for tetracyclines (64%; P<.001), clindamycin (61%; P<.001), sulfamethoxazole/trimethoprim (38%; P<.001), fluoroquinolones (38%; P<.001), and β-lactam/β-lactamase inhibitor combinations (28%; P<.001). The rate of positive C. difficile tests at the LTCF declined in the postintervention period relative to preintervention rates (P=.04).
CONCLUSIONS: Implementation of an LTCF ID service led to a significant reduction in total antimicrobial use. Bringing providers with ID expertise to the LTCF represents a new and effective means to achieve antimicrobial stewardship.

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Year:  2012        PMID: 23143354      PMCID: PMC4370223          DOI: 10.1086/668429

Source DB:  PubMed          Journal:  Infect Control Hosp Epidemiol        ISSN: 0899-823X            Impact factor:   3.254


  24 in total

1.  Segmented regression analysis of interrupted time series studies in medication use research.

Authors:  A K Wagner; S B Soumerai; F Zhang; D Ross-Degnan
Journal:  J Clin Pharm Ther       Date:  2002-08       Impact factor: 2.512

2.  Survey of antimicrobial stewardship practices in Nebraska long-term care facilities.

Authors:  Trevor Van Schooneveld; Hannah Miller; Harlan Sayles; Kristin Watkins; Philip W Smith
Journal:  Infect Control Hosp Epidemiol       Date:  2011-07       Impact factor: 3.254

3.  Colonization of skilled-care facility residents with antimicrobial-resistant pathogens.

Authors:  W E Trick; R A Weinstein; P L DeMarais; M J Kuehnert; W Tomaska; C Nathan; T W Rice; S K McAllister; L A Carson; W R Jarvis
Journal:  J Am Geriatr Soc       Date:  2001-03       Impact factor: 5.562

4.  Epidemics of diarrhea caused by a clindamycin-resistant strain of Clostridium difficile in four hospitals.

Authors:  S Johnson; M H Samore; K A Farrow; G E Killgore; F C Tenover; D Lyras; J I Rood; P DeGirolami; A L Baltch; M E Rafferty; S M Pear; D N Gerding
Journal:  N Engl J Med       Date:  1999-11-25       Impact factor: 91.245

5.  Antimicrobial use in long-term-care facilities. SHEA Long-Term-Care Committee.

Authors:  L E Nicolle; D W Bentley; R Garibaldi; E G Neuhaus; P W Smith
Journal:  Infect Control Hosp Epidemiol       Date:  2000-08       Impact factor: 3.254

Review 6.  The burden of infection in long-term care.

Authors:  L J Strausbaugh; C L Joseph
Journal:  Infect Control Hosp Epidemiol       Date:  2000-10       Impact factor: 3.254

Review 7.  Infectious diseases in the nursing home setting: challenges and opportunities for clinical investigation.

Authors:  Manisha Juthani-Mehta; Vincent J Quagliarello
Journal:  Clin Infect Dis       Date:  2010-10-15       Impact factor: 9.079

8.  Benchmarking risk-adjusted adult antibacterial drug use in 70 US academic medical center hospitals.

Authors:  Ron E Polk; Samuel F Hohmann; Sofia Medvedev; Omar Ibrahim
Journal:  Clin Infect Dis       Date:  2011-10-13       Impact factor: 9.079

9.  Emerging health care-associated infections in the geriatric population.

Authors:  L J Strausbaugh
Journal:  Emerg Infect Dis       Date:  2001 Mar-Apr       Impact factor: 6.883

10.  Multihospital outbreak of Clostridium difficile infection, Cleveland, Ohio, USA.

Authors:  Robin L P Jump; Michelle M Riggs; Ajay K Sethi; Michael J Pultz; Tracie Ellis-Reid; William Riebel; Dale N Gerding; Robert A Salata; Curtis J Donskey
Journal:  Emerg Infect Dis       Date:  2010-05       Impact factor: 6.883

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  48 in total

1.  Mixed-Methods Pilot Study to Assess Perceptions of Antimicrobial Stewardship in Nursing Homes.

Authors:  Rebecca R Carter; Michelle M Montpetite; Robin L P Jump
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2.  Clostridium difficile infection in older adults.

Authors:  Robin Lp Jump
Journal:  Aging health       Date:  2013-08-01

3.  Impact of Antimicrobial Stewardship on Physician Practice in a Geriatric Facility.

Authors:  Nina Kassett; Rosalind Sham; Rosanne Aleong; Daisy Yang; Michael Kirzner; Aidlee Craft
Journal:  Can J Hosp Pharm       Date:  2016-12-23

4.  Influences on the start, selection and duration of treatment with antibiotics in long-term care facilities.

Authors:  Nick Daneman; Michael A Campitelli; Vasily Giannakeas; Andrew M Morris; Chaim M Bell; Colleen J Maxwell; Lianne Jeffs; Peter C Austin; Susan E Bronskill
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5.  Antimicrobial use and drug-drug interactions among nursing home residents in Singapore: a multicentre prevalence study.

Authors:  Aysu Selcuk; Christine B Teng; Sui Yung Chan; Kai Zhen Yap
Journal:  Int J Clin Pharm       Date:  2018-07-27

6.  An online course improves nurses' awareness of their role as antimicrobial stewards in nursing homes.

Authors:  Brigid M Wilson; Sue Shick; Rebecca R Carter; Barbara Heath; Patricia A Higgins; Basia Sychla; Danielle M Olds; Robin L P Jump
Journal:  Am J Infect Control       Date:  2017-02-08       Impact factor: 2.918

7.  Financial impact of health care-associated infections: When money talks.

Authors:  Louis Valiquette; Claire Nour Abou Chakra; Kevin B Laupland
Journal:  Can J Infect Dis Med Microbiol       Date:  2014-03       Impact factor: 2.471

8.  Implementing an Antibiotic Stewardship Program: Guidelines by the Infectious Diseases Society of America and the Society for Healthcare Epidemiology of America.

Authors:  Tamar F Barlam; Sara E Cosgrove; Lilian M Abbo; Conan MacDougall; Audrey N Schuetz; Edward J Septimus; Arjun Srinivasan; Timothy H Dellit; Yngve T Falck-Ytter; Neil O Fishman; Cindy W Hamilton; Timothy C Jenkins; Pamela A Lipsett; Preeti N Malani; Larissa S May; Gregory J Moran; Melinda M Neuhauser; Jason G Newland; Christopher A Ohl; Matthew H Samore; Susan K Seo; Kavita K Trivedi
Journal:  Clin Infect Dis       Date:  2016-04-13       Impact factor: 9.079

9.  Aging, the Medical Subspecialties, and Career Development: Where We Were, Where We Are Going.

Authors:  Arti Hurria; Kevin P High; Lona Mody; Frances McFarland Horne; Marcus Escobedo; Jeffrey Halter; William Hazzard; Kenneth Schmader; Heidi Klepin; Sei Lee; Una E Makris; Michael W Rich; Stephanie Rogers; Jocelyn Wiggins; Rachael Watman; Jennifer Choi; Nancy Lundebjerg; Susan Zieman
Journal:  J Am Geriatr Soc       Date:  2017-01-16       Impact factor: 5.562

Review 10.  [Multiresistant gram-negative bacteria. A bacterial challenge of the twenty-first century].

Authors:  K Schröppel; R Riessen
Journal:  Med Klin Intensivmed Notfmed       Date:  2013-03-13       Impact factor: 0.840

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