Literature DB >> 23143258

Crystallization and diffraction of an Isl1-Ldb1 complex.

Morgan S Gadd1, David A Jacques, J Mitchell Guss, Jacqueline M Matthews.   

Abstract

A stable intramolecular complex comprising the LIM domains of the LIM-homeodomain protein Isl1 tethered to a peptide region of Ldb1 has been engineered, purified and crystallized. The orthorhombic crystals belonged to space group P222(1), with unit-cell parameters a=57.2, b=56.7, c=179.8 Å, and diffracted to 3.10 Å resolution.

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Year:  2012        PMID: 23143258      PMCID: PMC3515390          DOI: 10.1107/S1744309112040031

Source DB:  PubMed          Journal:  Acta Crystallogr Sect F Struct Biol Cryst Commun        ISSN: 1744-3091


  25 in total

Review 1.  The LIM domain: regulation by association.

Authors:  I Bach
Journal:  Mech Dev       Date:  2000-03-01       Impact factor: 1.882

2.  LIM factor Lhx3 contributes to the specification of motor neuron and interneuron identity through cell-type-specific protein-protein interactions.

Authors:  Joshua P Thaler; Soo-Kyung Lee; Linda W Jurata; Gordon N Gill; Samuel L Pfaff
Journal:  Cell       Date:  2002-07-26       Impact factor: 41.582

3.  Functional analysis of the nuclear LIM domain interactor NLI.

Authors:  L W Jurata; G N Gill
Journal:  Mol Cell Biol       Date:  1997-10       Impact factor: 4.272

4.  Solvent content of protein crystals.

Authors:  B W Matthews
Journal:  J Mol Biol       Date:  1968-04-28       Impact factor: 5.469

Review 5.  LIM-homeodomain genes in mammalian development and human disease.

Authors:  Chad S Hunter; Simon J Rhodes
Journal:  Mol Biol Rep       Date:  2005-06       Impact factor: 2.316

6.  Integrated FGF and BMP signaling controls the progression of progenitor cell differentiation and the emergence of pattern in the embryonic anterior pituitary.

Authors:  J Ericson; S Norlin; T M Jessell; T Edlund
Journal:  Development       Date:  1998-03       Impact factor: 6.868

7.  Implementing the LIM code: the structural basis for cell type-specific assembly of LIM-homeodomain complexes.

Authors:  Mugdha Bhati; Christopher Lee; Amy L Nancarrow; Mihwa Lee; Vanessa J Craig; Ingolf Bach; J Mitchell Guss; Joel P Mackay; Jacqueline M Matthews
Journal:  EMBO J       Date:  2008-06-26       Impact factor: 11.598

8.  Requirement for LIM homeobox gene Isl1 in motor neuron generation reveals a motor neuron-dependent step in interneuron differentiation.

Authors:  S L Pfaff; M Mendelsohn; C L Stewart; T Edlund; T M Jessell
Journal:  Cell       Date:  1996-01-26       Impact factor: 41.582

Review 9.  LIM-domain-binding protein 1: a multifunctional cofactor that interacts with diverse proteins.

Authors:  Jacqueline M Matthews; Jane E Visvader
Journal:  EMBO Rep       Date:  2003-12       Impact factor: 8.807

10.  Formation of Rathke's pouch requires dual induction from the diencephalon.

Authors:  N Takuma; H Z Sheng; Y Furuta; J M Ward; K Sharma; B L Hogan; S L Pfaff; H Westphal; S Kimura; K A Mahon
Journal:  Development       Date:  1998-12       Impact factor: 6.868

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  1 in total

1.  A structural basis for the regulation of the LIM-homeodomain protein islet 1 (Isl1) by intra- and intermolecular interactions.

Authors:  Morgan S Gadd; David A Jacques; Ivan Nisevic; Vanessa J Craig; Ann H Kwan; J Mitchell Guss; Jacqueline M Matthews
Journal:  J Biol Chem       Date:  2013-06-09       Impact factor: 5.157

  1 in total

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