Literature DB >> 23142955

Use of injectable spasticity management agents in a cancer center.

Jack Fu1, Carolina Gutiérrez, Eduardo Bruera, Ying Guo, Shana Palla.   

Abstract

PURPOSE: This study aims to analyze the utilization and effectiveness of injectable spasticity medications by the physiatry team at a referral-based tertiary cancer center.
METHODS: A retrospective review and analysis of patient and injection characteristics were obtained from patients who had received onabotulinum toxin or phenol nerve block injections from December 1, 2007 through January 31, 2012. Out of 3,724 physiatry consultations during this period, 20 (less than 1 %) different cancer patients received a total of 54 total procedures.
RESULTS: The majority of patients (17/20, 85 %) had a positive response to the injection. A positive response to the injection was defined by: (1) if the patient qualified to receive and was given another injection or (2) if there is a record of improvement if they did not receive another injection. A total of ten of 20 (50 %) patients received only one injection. Of these, seven of ten (70 %) reported a positive response to the injected agent. Those with only one injection tended to live farther away and die sooner. Four of 54 (7 %) injection procedures resulted in undesirable reported side effects (two for phenol, two for botulinum toxin). Nine of 54 (17 %) procedures occurred while the patients were on a chemotherapy protocol. All patients were injected at least 1 year out from initial diagnosis.

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Year:  2012        PMID: 23142955      PMCID: PMC3586383          DOI: 10.1007/s00520-012-1651-0

Source DB:  PubMed          Journal:  Support Care Cancer        ISSN: 0941-4355            Impact factor:   3.603


  31 in total

1.  MANAGEMENT OF SPASTICITY BY SELECTIVE PERIPHERAL NERVE BLOCK WITH DILUTE PHENOL SOLUTIONS IN CLINICAL REHABILITATION.

Authors:  A A KHALILI; M H HARMEL; S FORSTER; J G BENTON
Journal:  Arch Phys Med Rehabil       Date:  1964-10       Impact factor: 3.966

2.  Spasticity after traumatic spinal cord injury: nature, severity, and location.

Authors:  C Sköld; R Levi; A Seiger
Journal:  Arch Phys Med Rehabil       Date:  1999-12       Impact factor: 3.966

3.  A randomized, double-blind, placebo-controlled study of the efficacy and safety of botulinum toxin type A in upper limb spasticity in patients with stroke.

Authors:  A M Bakheit; S Pittock; A P Moore; M Wurker; S Otto; F Erbguth; L Coxon
Journal:  Eur J Neurol       Date:  2001-11       Impact factor: 6.089

4.  Barriers to rehabilitative care for young breast cancer survivors: a qualitative understanding.

Authors:  Baukje Miedema; Julie Easley
Journal:  Support Care Cancer       Date:  2011-05-28       Impact factor: 3.603

5.  A database of self-reported secondary medical problems among VA spinal cord injury patients: its role in clinical care and management.

Authors:  James S Walter; Jerome Sacks; Raslan Othman; Alexander Z Rankin; Bernard Nemchausky; Rani Chintam; John S Wheeler
Journal:  J Rehabil Res Dev       Date:  2002 Jan-Feb

6.  Spasticity after stroke: its occurrence and association with motor impairments and activity limitations.

Authors:  Disa K Sommerfeld; Elsy U-B Eek; Anna-Karin Svensson; Lotta Widén Holmqvist; Magnus H von Arbin
Journal:  Stroke       Date:  2003-12-18       Impact factor: 7.914

7.  Botulinum toxin infiltration for pain control after mastectomy and expander reconstruction.

Authors:  Rakhshanda Layeeque; Julio Hochberg; Eric Siegel; Kelly Kunkel; Julie Kepple; Ronda S Henry-Tillman; Melinda Dunlap; John Seibert; V Suzanne Klimberg
Journal:  Ann Surg       Date:  2004-10       Impact factor: 12.969

Review 8.  Management of spasticity.

Authors:  R T Katz
Journal:  Am J Phys Med Rehabil       Date:  1988-06       Impact factor: 2.159

9.  Alcohol neurolysis of tibial nerve motor branches to the gastrocnemius muscle to treat ankle spasticity in patients with hemiplegic stroke.

Authors:  Sung Ho Jang; Sang Ho Ahn; Sung Min Park; Seong Ho Kim; Kang Hee Lee; Zee Ihn Lee
Journal:  Arch Phys Med Rehabil       Date:  2004-03       Impact factor: 3.966

10.  Prevalence of spasticity post stroke.

Authors:  C L Watkins; M J Leathley; J M Gregson; A P Moore; T L Smith; A K Sharma
Journal:  Clin Rehabil       Date:  2002-08       Impact factor: 3.477

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  1 in total

1.  What are the attitudes and beliefs of oncologists regarding potential cancer rehabilitation in a tertiary cancer center?

Authors:  G J Francis; J B Fu
Journal:  Rehabil Oncol       Date:  2019-10
  1 in total

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