Literature DB >> 23141986

Recent developments on polysaccharide-based chiral stationary phases for liquid-phase separation of enantiomers.

Bezhan Chankvetadze1.   

Abstract

This paper summarizes recent developments in the synthesis, application and mechanistic studies on polysaccharide-based chiral stationary phases (CSPs) for liquid phase separation techniques. Together with applications in conventional high-performance liquid chromatography (HPLC) applications in nano-liquid chromatography (nano-LC), capillary electrochromatography (CEC), super/sub-critical fluid chromatography (SFC) and preparative and product scale separations are also summarized. In the final part of the overview mechanistic aspects and some unusual effects observed in HPLC with these materials are shortly discussed and the author's view regarding future trends in this field is provided.
Copyright © 2012 Elsevier B.V. All rights reserved.

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Year:  2012        PMID： 23141986     DOI： 10.1016/j.chroma.2012.10.033

Source DB:  PubMed          Journal:  J Chromatogr A        ISSN： 0021-9673            Impact factor:   4.759


  13 in total

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