PURPOSE: Inhalation of ylang-ylang aroma has been shown to reduce the auditory P300, an event-related potential thought to reflect higher-order processing. Because olfactory function is sometimes disturbed in temporal lobe epilepsy (TLE), the objective of the present study was to determine whether the effect of ylang-ylang aroma on the auditory P300 was impaired in patients with TLE. METHOD: Fourteen subjects with TLE and 14 healthy controls participated in this study. Electroencephalograms were recorded during an auditory oddball task, and ylang-ylang aroma or odorless air was delivered through a mask. RESULTS: We found that the ylang-ylang aroma prolonged the latencies of P300 in both groups. The ylang-ylang aroma significantly reduced the P300 amplitudes of healthy subjects as described previously. However, in TLE patients, the P300 was unaffected by the aroma. CONCLUSION: The current results show that exposure to the ylang-ylang aroma reduced information processing resources in healthy subjects but had limited effects in patients with TLE. We suggest that impaired higher-order olfactory processing in TLE patients may inhibit the effects of the ylang-ylang aroma on the P300.
PURPOSE: Inhalation of ylang-ylang aroma has been shown to reduce the auditory P300, an event-related potential thought to reflect higher-order processing. Because olfactory function is sometimes disturbed in temporal lobe epilepsy (TLE), the objective of the present study was to determine whether the effect of ylang-ylang aroma on the auditory P300 was impaired in patients with TLE. METHOD: Fourteen subjects with TLE and 14 healthy controls participated in this study. Electroencephalograms were recorded during an auditory oddball task, and ylang-ylang aroma or odorless air was delivered through a mask. RESULTS: We found that the ylang-ylang aroma prolonged the latencies of P300 in both groups. The ylang-ylang aroma significantly reduced the P300 amplitudes of healthy subjects as described previously. However, in TLEpatients, the P300 was unaffected by the aroma. CONCLUSION: The current results show that exposure to the ylang-ylang aroma reduced information processing resources in healthy subjects but had limited effects in patients with TLE. We suggest that impaired higher-order olfactory processing in TLEpatients may inhibit the effects of the ylang-ylang aroma on the P300.
Authors: Kiran Khurshid; Andrew J D Crow; Petra E Rupert; Nancy L Minniti; Melissa A Carswell; Dawn J Mechanic-Hamilton; Vidyulata Kamath; Richard L Doty; Paul J Moberg; David R Roalf Journal: Neuropsychol Rev Date: 2019-05-29 Impact factor: 7.444
Authors: Loh Teng Hern Tan; Learn Han Lee; Wai Fong Yin; Chim Kei Chan; Habsah Abdul Kadir; Kok Gan Chan; Bey Hing Goh Journal: Evid Based Complement Alternat Med Date: 2015-07-30 Impact factor: 2.629
Authors: Jieqiong Liu; Shi Cai; Danni Chen; Ke Wu; Yang Liu; Ruqian Zhang; Mei Chen; Xianchun Li Journal: Behav Neurol Date: 2019-10-15 Impact factor: 3.342