BACKGROUND: The aim of the present study was to explore the association between Parkinson's disease (PD) clinical characteristics and cardiac autonomic control across sleep stages. METHODS: Frequency-domain heart rate variability (HRV) measures were estimated in 18 PD patients undergoing a night of polysomnography. RESULTS: Significant relationships were found between PD severity and nocturnal HRV indices. The associations were restricted to rapid eye movement (R) sleep. CONCLUSIONS: The progressive nocturnal cardiac autonomic impairment occurring with more severe PD can be subclinical emerging only during conditions requiring active modulation of physiological functions such as R-sleep.
BACKGROUND: The aim of the present study was to explore the association between Parkinson's disease (PD) clinical characteristics and cardiac autonomic control across sleep stages. METHODS: Frequency-domain heart rate variability (HRV) measures were estimated in 18 PDpatients undergoing a night of polysomnography. RESULTS: Significant relationships were found between PD severity and nocturnal HRV indices. The associations were restricted to rapid eye movement (R) sleep. CONCLUSIONS: The progressive nocturnal cardiac autonomic impairment occurring with more severe PD can be subclinical emerging only during conditions requiring active modulation of physiological functions such as R-sleep.
Authors: T H Haapaniemi; V Pursiainen; J T Korpelainen; H V Huikuri; K A Sotaniemi; V V Myllylä Journal: J Neurol Neurosurg Psychiatry Date: 2001-03 Impact factor: 10.154
Authors: Ariel B Neikrug; Lianqi Liu; Julie A Avanzino; Jeanne E Maglione; Loki Natarajan; Lenette Bradley; Alex Maugeri; Jody Corey-Bloom; Barton W Palmer; Jose S Loredo; Sonia Ancoli-Israel Journal: Sleep Date: 2014-01-01 Impact factor: 5.849