Literature DB >> 23140351

Marine natural products and related compounds as anticancer agents: an overview of their clinical status.

Karina Petit1, Jean-François Biard.   

Abstract

Marine ecosystems constitute a huge reservoir of biologically active secondary metabolites. Consequently during the last past few decades, several marine-derived molecules have been approved for anticancer treatment or are under clinical trials. This review reports the present state of the art of the sixteen molecules approved or currently on the clinical pipeline for anticancer chemotherapy. The molecules are classified according to their current status in the phase (approved / phase IV / phase III / phase II / phase I) and data are updated to April 2012.

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Year:  2013        PMID： 23140351     DOI： 10.2174/1871520611313040010

Source DB:  PubMed          Journal:  Anticancer Agents Med Chem        ISSN： 1871-5206            Impact factor:   2.505


  10 in total

Review 1.  Can Some Marine-Derived Fungal Metabolites Become Actual Anticancer Agents?

Authors:  Nelson G M Gomes; Florence Lefranc; Anake Kijjoa; Robert Kiss
Journal:  Mar Drugs       Date:  2015-06-19       Impact factor: 5.118

2.  Polypeptide Fraction from Arca subcrenata Induces Apoptosis and G2/M Phase Arrest in HeLa Cells via ROS-Mediated MAPKs Pathways.

Authors:  Xianjing Hu; Zhang Zhang; Ting Liu; Liyan Song; Jianhua Zhu; Zhongyi Guo; Jinghua Cai; Rongmin Yu
Journal:  Evid Based Complement Alternat Med       Date:  2015-05-21       Impact factor: 2.629

3.  Bioactive Polycyclic Quinones from Marine Streptomyces sp. 182SMLY.

Authors:  Ying Liang; Xin Xie; Lu Chen; Shilun Yan; Xuewei Ye; Komal Anjum; Haocai Huang; Xiaoyuan Lian; Zhizhen Zhang
Journal:  Mar Drugs       Date:  2016-01-06       Impact factor: 5.118

4.  Anti-glioma Natural Products Downregulating Tumor Glycolytic Enzymes from Marine Actinomycete Streptomyces sp. ZZ406.

Authors:  Mengxuan Chen; Weiyun Chai; Tengfei Song; Mingzhu Ma; Xiao-Yuan Lian; Zhizhen Zhang
Journal:  Sci Rep       Date:  2018-01-08       Impact factor: 4.379

Review 5.  Nonribosomal Peptides from Marine Microbes and Their Antimicrobial and Anticancer Potential.

Authors:  Shivankar Agrawal; Debabrata Acharya; Alok Adholeya; Colin J Barrow; Sunil K Deshmukh
Journal:  Front Pharmacol       Date:  2017-11-21       Impact factor: 5.810

6.  Toxicity and Potential Pharmacological Activities in the Persian Gulf Venomous Sea Anemone, Stichodactyla haddoni.

Authors:  Ziba Moghadasi; Shahla Jamili; Delavar Shahbazadeh; Kamran Pooshang Bagheri
Journal:  Iran J Pharm Res       Date:  2018       Impact factor: 1.696

7.  Antiproliferative cyclodepsipeptides from the marine actinomycete Streptomyces sp. P11-23B downregulating the tumor metabolic enzymes of glycolysis, glutaminolysis, and lipogenesis.

Authors:  Xuewei Ye; Komal Anjum; Tengfei Song; Wenling Wang; Ying Liang; Mengxuan Chen; Haocai Huang; Xiao-Yuan Lian; Zhizhen Zhang
Journal:  Phytochemistry       Date:  2016-12-31       Impact factor: 4.072

8.  New 1,2,3-Triazoles from (R)-Carvone: Synthesis, DFT Mechanistic Study and In Vitro Cytotoxic Evaluation.

Authors:  Ali Oubella; Abdoullah Bimoussa; Abdellah N'ait Oussidi; Mourad Fawzi; Aziz Auhmani; Hamid Morjani; Abdelkhalek Riahi; M'hamed Esseffar; Carol Parish; Moulay Youssef Ait Itto
Journal:  Molecules       Date:  2022-01-25       Impact factor: 4.411

Review 9.  Marine-sourced anti-cancer and cancer pain control agents in clinical and late preclinical development.

Authors:  David J Newman; Gordon M Cragg
Journal:  Mar Drugs       Date:  2014-01-14       Impact factor: 5.118

Review 10.  Marine sponge derived natural products between 2001 and 2010: trends and opportunities for discovery of bioactives.

Authors:  Mohammad Ferdous Mehbub; Jie Lei; Christopher Franco; Wei Zhang
Journal:  Mar Drugs       Date:  2014-08-19       Impact factor: 5.118
  10 in total

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