Literature DB >> 23139545

Keloidoscope: in search for the ideal treatment of keloids.

Sonal Anchlia1, Krishna Shama Rao, Krishnamurthy Bonanthaya, Deepak Vohra.   

Abstract

Although keloids were recognised in the Smith Papyrus of ancient times, the precise definition, cause and management have remained elusive. Several forms of treatment have been used with varying success.Objectives This study assesses and compares the value of intralesional steroid (Triamcinolone acetonide 40mg/ml), cryotherapy and cryotherapy with intralesional steroid in the treatment of keloids.Methodology 33 patients were studied, 11 each in the three arms and the volume of the keloids was recorded using wax patterns of alginate impressions of the keloids to note the change in size postoperatively.Results The best average percentage response was observed is patients who received both Cryotherapy (CRY) and Intralesional Steroid (ILS) (69.02%) followed by patients who received only intralesional steroid (43.98%). Among the patients who received only cryotherapy, the average percentage response was only 39.24%. 72.73% patients who received intralesional steroid with cryotherapy showed more than 50% improvement (good response) while only 9.09% patients who received intralesional steroid alone and cryotherapy alone showed similar improvement.Conclusion In patients with keloids good response can be obtained with CRY with ILS as compared to ILS alone and CRY alone.

Entities:  

Keywords:  Cryotherapy; Intralesional steroids; Keloids

Year:  2010        PMID: 23139545      PMCID: PMC3454089          DOI: 10.1007/s12663-009-0087-7

Source DB:  PubMed          Journal:  J Maxillofac Oral Surg        ISSN: 0972-8270


  11 in total

Review 1.  Keloids and hypertrophic scars: review and treatment strategies.

Authors:  S S Urioste; K A Arndt; J S Dover
Journal:  Semin Cutan Med Surg       Date:  1999-06

Review 2.  Keloids and hypertrophic scars: a comprehensive review.

Authors:  W B Rockwell; I K Cohen; H P Ehrlich
Journal:  Plast Reconstr Surg       Date:  1989-11       Impact factor: 4.730

3.  Intra- and postoperative steroid injections for keloids and hypertrophic scars.

Authors:  Y W Tang
Journal:  Br J Plast Surg       Date:  1992-07

Review 4.  Laser treatment of hypertrophic scars, keloids, and striae.

Authors:  T S Alster
Journal:  Dermatol Clin       Date:  1997-07       Impact factor: 3.478

5.  Keloids.

Authors:  B Berman; H C Bieley
Journal:  J Am Acad Dermatol       Date:  1995-07       Impact factor: 11.527

6.  Treatment of keloid sternotomy scars with 585 nm flashlamp-pumped pulsed-dye laser.

Authors:  T S Alster; C M Williams
Journal:  Lancet       Date:  1995-05-13       Impact factor: 79.321

Review 7.  Scars and keloids.

Authors:  J C Murray
Journal:  Dermatol Clin       Date:  1993-10       Impact factor: 3.478

8.  Use of cryotherapy in the treatment of keloids.

Authors:  L Rusciani; G Rossi; R Bono
Journal:  J Dermatol Surg Oncol       Date:  1993-06

Review 9.  Cutaneous scars: Part I.

Authors:  W J Sahl; H Clever
Journal:  Int J Dermatol       Date:  1994-10       Impact factor: 2.736

10.  Control of connective tissue metabolism by lasers: recent developments and future prospects.

Authors:  R P Abergel; C A Meeker; T S Lam; R M Dwyer; M A Lesavoy; J Uitto
Journal:  J Am Acad Dermatol       Date:  1984-12       Impact factor: 11.527

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