Literature DB >> 23137729

Life-event specificity: bipolar disorder compared with unipolar depression.

Georgina M Hosang1, Ania Korszun, Lisa Jones, Ian Jones, Peter McGuffin, Anne E Farmer.   

Abstract

BACKGROUND: Little is known about the impact of different types of stressful events (for example divorce v. bereavement) on unipolar depression compared with bipolar disorder. Inconsistencies exist concerning the association between independent events (beyond an individual's control, such as bereavement) and bipolar disorder. AIMS: To examine the role of specific, independent and dependent events in mood disorders.
METHOD: Life-event information was collected from 512 people with bipolar disorder, 1448 people with unipolar depression and over 600 controls.
RESULTS: Various events were associated with unipolar depression and bipolar disorder, but some event specificity was detected. For example, financial crisis was more strongly related to bipolar disorder rather than unipolar depression. Independent events were only related to unipolar depression and not bipolar disorder.
CONCLUSIONS: The events that were linked to bipolar disorder and unipolar depression were similar. Independent events were not associated with bipolar episodes, suggesting that life stress may be a consequence of, rather than a trigger for, bipolar episodes.

Entities:  

Mesh:

Year:  2012        PMID: 23137729     DOI: 10.1192/bjp.bp.112.111047

Source DB:  PubMed          Journal:  Br J Psychiatry        ISSN: 0007-1250            Impact factor:   9.319


  10 in total

Review 1.  The Influence of Trauma, Life Events, and Social Relationships on Bipolar Depression.

Authors:  Sheri L Johnson; Amy K Cuellar; Anda Gershon
Journal:  Psychiatr Clin North Am       Date:  2015-12-22

2.  Neuronal nitric oxide synthase (NOS1) polymorphisms interact with financial hardship to affect depression risk.

Authors:  Jane E Sarginson; J F William Deakin; Ian M Anderson; Darragh Downey; Emma Thomas; Rebecca Elliott; Gabriella Juhasz
Journal:  Neuropsychopharmacology       Date:  2014-06-11       Impact factor: 7.853

3.  Putative transcriptomic biomarkers in the inflammatory cytokine pathway differentiate major depressive disorder patients from control subjects and bipolar disorder patients.

Authors:  Timothy R Powell; Peter McGuffin; Ursula M D'Souza; Sarah Cohen-Woods; Georgina M Hosang; Charlotte Martin; Keith Matthews; Richard K Day; Anne E Farmer; Katherine E Tansey; Leonard C Schalkwyk
Journal:  PLoS One       Date:  2014-03-11       Impact factor: 3.240

4.  Stressful Life Events and Relapse in Bipolar Affective Disorder: A Cross-Sectional Study from a Tertiary Care Center of Southern India.

Authors:  Sivin P Sam; A Nisha; P Joseph Varghese
Journal:  Indian J Psychol Med       Date:  2019 Jan-Feb

5.  The relationship between independent and dependent life events and depression symptoms in Sri Lanka: a twin and singleton study.

Authors:  Helena M S Zavos; Bethan Dalton; Kaushalya Jayaweera; Lisa Harber-Aschan; Gayani Pannala; Anushka Adikari; Stephani L Hatch; Sisira Siribaddana; Athula Sumathipala; Matthew Hotopf; Frühling V Rijsdijk
Journal:  Soc Psychiatry Psychiatr Epidemiol       Date:  2019-09-03       Impact factor: 4.328

6.  Differences in the Clinical Picture in Women with a Depressive Episode in the Course of Unipolar and Bipolar Disorder.

Authors:  Karolina Bilska; Joanna Pawlak; Paweł Kapelski; Beata Narożna; Przemysław Zakowicz; Aleksandra Szczepankiewicz; Maria Skibińska; Monika Dmitrzak-Węglarz
Journal:  J Clin Med       Date:  2021-02-10       Impact factor: 4.241

7.  Psychosocial markers of age at onset in bipolar disorder: a machine learning approach.

Authors:  Sorcha Bolton; Dan W Joyce; Katherine Gordon-Smith; Lisa Jones; Ian Jones; John Geddes; Kate E A Saunders
Journal:  BJPsych Open       Date:  2022-07-18

8.  Childhood trauma in bipolar disorder.

Authors:  Stuart Watson; Peter Gallagher; Dominic Dougall; Richard Porter; Joanna Moncrieff; I Nicol Ferrier; Allan H Young
Journal:  Aust N Z J Psychiatry       Date:  2013-12-16       Impact factor: 5.744

Review 9.  Interaction between stress and the BDNF Val66Met polymorphism in depression: a systematic review and meta-analysis.

Authors:  Georgina M Hosang; Celia Shiles; Katherine E Tansey; Peter McGuffin; Rudolf Uher
Journal:  BMC Med       Date:  2014-01-16       Impact factor: 8.775

Review 10.  Environmental factors, life events, and trauma in the course of bipolar disorder.

Authors:  Fanny Aldinger; Thomas G Schulze
Journal:  Psychiatry Clin Neurosci       Date:  2016-09-21       Impact factor: 5.188

  10 in total

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