Literature DB >> 231360

Synaptic function in the nervous system: a theory and its application.

J Dempsher.   

Abstract

The objective of this paper is to present a new theory of synaptic function in the nervous system. The basis for this theory is the experimental demonstration that a nerve impulse assumes five different forms as it advances through the synaptic region, and that five basic mathematical operations have been identified as being involved in the transformation of one form into another form. As a result of these data, the synaptic region is regarded as a functional unit where information coming to it is unpacked, processed, stored, and retrieved for transit to another synaptic region or effector site. The data also suggests that a nerve impulse is a bolus of energy, therefore, without substance; that it contains information coded in its shape or form; that it is precisely described mathematically. Furthermore, the data suggests synaptic regions process these nerve impulses by applying mathematical operations to them; that function in the synaptic region is highly stereotyped (programmed); that chemical substances are associated with the mathematical operations. The basic approach of this theory is to regard a significant portion of the nervous system as an 'interface' between the external universe and man himself. As an interface, the nervous system receives and processes information from both the external universe and man himself in a programmed manner. The interface functions by converting the information it receives into a bolus of energy, the nerve impulse, then processes the bolus by converting it into numbers or functions and applying mathematical operation to it.

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Year:  1979        PMID: 231360     DOI: 10.1007/bf00046806

Source DB:  PubMed          Journal:  Acta Biotheor        ISSN: 0001-5342            Impact factor:   1.774


  13 in total

1.  STRUCTURAL AND FUNCTIONAL CHANGES IN THE FROG SYMPATHETIC GANGLION FOLLOWING CUTTING OF THE PRESYNAPTIC NERVE FIBRES.

Authors:  C C HUNT; P G NELSON
Journal:  J Physiol       Date:  1965-03       Impact factor: 5.182

2.  On the quantal release of the transmitter at a sympathetic synapse.

Authors:  J G BLACKMAN; B L GINSBORG; C RAY
Journal:  J Physiol       Date:  1963-07       Impact factor: 5.182

3.  A possible role of an inhibitory system in virus-infected sympathetic ganglia of the rat.

Authors:  J DEMPSHER; T TOKUMARU; J ZABARA
Journal:  J Physiol       Date:  1959-06-11       Impact factor: 5.182

4.  A study of presynaptic slow potentials in virus-infected sympathetic ganglia of the rat.

Authors:  J DEMPSHER; J ZABARA
Journal:  J Physiol       Date:  1960-05       Impact factor: 5.182

5.  General problems of drugs actions on bioelectric phenomena.

Authors:  H GRUNDFEST
Journal:  Ann N Y Acad Sci       Date:  1957-03-14       Impact factor: 5.691

6.  The role of acetylcholine in virus-infected sympathetic ganglia.

Authors:  J DEMPSHER; W K RIKER
Journal:  J Physiol       Date:  1957-11-14       Impact factor: 5.182

7.  Physiological changes in sympathetic ganglia infected with pseudorabies virus.

Authors:  J DEMPSHER; M G LARRABEE; F B BANG; D BODIAN
Journal:  Am J Physiol       Date:  1955-07

8.  Synaptic potentials and transmission in sympathetic ganglion.

Authors:  J C Eccles
Journal:  J Physiol       Date:  1943-03-25       Impact factor: 5.182

9.  Spontaneous subthreshold activity at motor nerve endings.

Authors:  P FATT; B KATZ
Journal:  J Physiol       Date:  1952-05       Impact factor: 5.182

Review 10.  Generation of slow inhibitory and excitatory postsynaptic potentials.

Authors:  B Libet
Journal:  Fed Proc       Date:  1970 Nov-Dec
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  4 in total

1.  Integration of function in the nervous system - a new theory.

Authors:  J Dempsher
Journal:  Acta Biotheor       Date:  1979       Impact factor: 1.774

2.  Basic function in the nervous system - a unified theory.

Authors:  J Dempsher
Journal:  Acta Biotheor       Date:  1982       Impact factor: 1.774

3.  The nerve impulse in the axon--a new theory.

Authors:  J Dempsher
Journal:  Acta Biotheor       Date:  1981       Impact factor: 1.774

4.  A bio-physical basis of mathematics in synaptic function of the nervous system: a theory.

Authors:  J Dempsher
Journal:  Acta Biotheor       Date:  1980       Impact factor: 1.774

  4 in total

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