Literature DB >> 23135516

Before epilepsy unfolds: finding the epileptogenesis switch.

Annamaria Vezzani1.   

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Year:  2012        PMID： 23135516     DOI： 10.1038/nm.2982

Source DB:  PubMed          Journal:  Nat Med        ISSN： 1078-8956            Impact factor:   53.440


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  17 in total

1.  Pharmacological inhibition of the mammalian target of rapamycin pathway suppresses acquired epilepsy.

Authors:  Xiaoxing Huang; Hailong Zhang; Jun Yang; Jingfan Wu; John McMahon; Yufan Lin; Zhonglian Cao; Michael Gruenthal; Yunfei Huang
Journal:  Neurobiol Dis       Date:  2010-05-26       Impact factor: 5.996

Review 2.  Mammalian target of rapamycin (mTOR) inhibition: potential for antiseizure, antiepileptogenic, and epileptostatic therapy.

Authors:  Robin C C Ryther; Michael Wong
Journal:  Curr Neurol Neurosci Rep       Date:  2012-08       Impact factor: 5.081

3.  Single-cell Tsc1 knockout during corticogenesis generates tuber-like lesions and reduces seizure threshold in mice.

Authors:  David M Feliciano; Tiffany Su; Jean Lopez; Jean-Claude Platel; Angélique Bordey
Journal:  J Clin Invest       Date:  2011-03-14       Impact factor: 14.808

4.  Regulation of cell death and epileptogenesis by the mammalian target of rapamycin (mTOR): a double-edged sword?

Authors:  Ling-Hui Zeng; Sharon McDaniel; Nicholas R Rensing; Michael Wong
Journal:  Cell Cycle       Date:  2010-06-15       Impact factor: 4.534

Review 5.  mTOR: A pathogenic signaling pathway in developmental brain malformations.

Authors:  Peter B Crino
Journal:  Trends Mol Med       Date:  2011-09-02       Impact factor: 11.951

6.  The mammalian target of rapamycin signaling pathway mediates epileptogenesis in a model of temporal lobe epilepsy.

Authors:  Ling-Hui Zeng; Nicholas R Rensing; Michael Wong
Journal:  J Neurosci       Date:  2009-05-27       Impact factor: 6.167

7.  mTor is required for hypertrophy of Pten-deficient neuronal soma in vivo.

Authors:  Chang-Hyuk Kwon; Xiaoyan Zhu; Junyuan Zhang; Suzanne J Baker
Journal:  Proc Natl Acad Sci U S A       Date:  2003-10-08       Impact factor: 11.205

8.  Rapamycin reduces seizure frequency in tuberous sclerosis complex.

Authors:  Jennifer Muncy; Ian J Butler; Mary Kay Koenig
Journal:  J Child Neurol       Date:  2009-01-16       Impact factor: 1.987

Review 9.  Finding a better drug for epilepsy: the mTOR pathway as an antiepileptogenic target.

Authors:  Aristea S Galanopoulou; Jan A Gorter; Carlos Cepeda
Journal:  Epilepsia       Date:  2012-05-11       Impact factor: 5.864

10.  The interaction between early life epilepsy and autistic-like behavioral consequences: a role for the mammalian target of rapamycin (mTOR) pathway.

Authors:  Delia M Talos; Hongyu Sun; Xiangping Zhou; Erin C Fitzgerald; Michele C Jackson; Peter M Klein; Victor J Lan; Annelise Joseph; Frances E Jensen
Journal:  PLoS One       Date:  2012-05-02       Impact factor: 3.240
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  11 in total

Review 1.  Epilepsy associated tumors: Review article.

Authors:  Marco Giulioni; Gianluca Marucci; Matteo Martinoni; Anna Federica Marliani; Francesco Toni; Fiorina Bartiromo; Lilia Volpi; Patrizia Riguzzi; Francesca Bisulli; Ilaria Naldi; Roberto Michelucci; Agostino Baruzzi; Paolo Tinuper; Guido Rubboli
Journal:  World J Clin Cases       Date:  2014-11-16       Impact factor: 1.337

Review 2.  New avenues for anti-epileptic drug discovery and development.

Authors:  Wolfgang Löscher; Henrik Klitgaard; Roy E Twyman; Dieter Schmidt
Journal:  Nat Rev Drug Discov       Date:  2013-09-20       Impact factor: 84.694

Review 3.  Epilepsy related to developmental tumors and malformations of cortical development.

Authors:  Eleonora Aronica; Peter B Crino
Journal:  Neurotherapeutics       Date:  2014-04       Impact factor: 7.620

4.  Connectivity Mapping Using a Novel sv2a Loss-of-Function Zebrafish Epilepsy Model as a Powerful Strategy for Anti-epileptic Drug Discovery.

Authors:  Yifan Zhang; Lise Heylen; Michèle Partoens; James D Mills; Rafal M Kaminski; Patrice Godard; Michel Gillard; Peter A M de Witte; Aleksandra Siekierska
Journal:  Front Mol Neurosci       Date:  2022-05-24       Impact factor: 6.261

Review 5.  Immunity, Ion Channels and Epilepsy.

Authors:  Tsang-Shan Chen; Ming-Chi Lai; Huai-Ying Ingrid Huang; Sheng-Nan Wu; Chin-Wei Huang
Journal:  Int J Mol Sci       Date:  2022-06-09       Impact factor: 6.208

Review 6.  Searching for the ideal antiepileptogenic agent in experimental models: single treatment versus combinatorial treatment strategies.

Authors:  H Steve White; Wolfgang Löscher
Journal:  Neurotherapeutics       Date:  2014-04       Impact factor: 7.620

Review 7.  Pharmacological and Therapeutic Approaches in the Treatment of Epilepsy.

Authors:  Shampa Ghosh; Jitendra Kumar Sinha; Tarab Khan; Kuramkote Shivanna Devaraju; Prabhakar Singh; Kumar Vaibhav; Pankaj Gaur
Journal:  Biomedicines       Date:  2021-04-25

8.  Dynamic Susceptibility Contrast Enhanced (DSC) MRI Perfusion and Plasma Cytokine Levels in Patients after Tonic-clonic Seizures.

Authors:  Tatjana Filipovic; Katarina Surlan Popovic; Alojz Ihan; David Bozidar Vodusek
Journal:  Radiol Oncol       Date:  2017-08-14       Impact factor: 2.991

Review 9.  Pharmacogenomics in epilepsy.

Authors:  Simona Balestrini; Sanjay M Sisodiya
Journal:  Neurosci Lett       Date:  2017-01-10       Impact factor: 3.046

10.  Dysfunctional epileptic neuronal circuits and dysmorphic dendritic spines are mitigated by platelet-activating factor receptor antagonism.

Authors:  Alberto E Musto; Robert F Rosencrans; Chelsey P Walker; Surjyadipta Bhattacharjee; Chittalsinh M Raulji; Ludmila Belayev; Zhide Fang; William C Gordon; Nicolas G Bazan
Journal:  Sci Rep       Date:  2016-07-22       Impact factor: 4.379
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