Literature DB >> 23135346

An efficient organocatalytic enantioselective synthesis of spironitrocyclopropanes.

Utpal Das1, Yi-Ling Tsai, Wenwei Lin.   

Abstract

An organocatalytic asymmetric synthesis of spironitrocyclopropanes has been demonstrated starting from 2-arylidene-1,3-indandiones and bromonitroalkanes catalyzed by a cinchona-derived bifunctional organocatalyst. The products were obtained with excellent enantioselectivities, diastereoselectivities and with good yields.

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Year:  2013        PMID： 23135346     DOI： 10.1039/c2ob26943k

Source DB:  PubMed          Journal:  Org Biomol Chem        ISSN： 1477-0520            Impact factor:   3.876


  5 in total

1.  Enantioselective Synthesis of β-Fluoro Amines via β-Amino α-Fluoro Nitroalkanes and a Traceless Activating Group Strategy.

Authors:  Brandon A Vara; Jeffrey N Johnston
Journal:  J Am Chem Soc       Date:  2016-10-17       Impact factor: 15.419

Review 2.  The molecular diversity scope of 1,3-indandione in organic synthesis.

Authors:  Shima Asadi; Ghodsi Mohammadi Ziarani
Journal:  Mol Divers       Date:  2015-05-10       Impact factor: 2.943

3.  Rhodium-catalyzed enantioselective cyclopropanation of electron deficient alkenes.

Authors:  Hengbin Wang; David M Guptill; Adrian Varela Alvarez; Djamaladdin G Musaev; Huw M L Davies
Journal:  Chem Sci       Date:  2013-07       Impact factor: 9.825

4.  [3+2] regioselective annulation reaction of 2-arylidene-1,3-indandiones towards synthesis of spirocyclopentenes: understanding the mechanism of γ-attack vs. α-attack using DFT studies.

Authors:  Shaik Anwar; Li-Tzu Lin; V Srinivasadesikan; Veera Babu Gudise; Kwunmin Chen
Journal:  RSC Adv       Date:  2021-12-01       Impact factor: 4.036

5.  Synthesis of Novel Spiro-Tetrahydroquinoline Derivatives and Evaluation of Their Pharmacological Effects on Wound Healing.

Authors:  Yan-Cheng Liou; Yan-An Lin; Ke Wang; Juan-Cheng Yang; Yeong-Jiunn Jang; Wenwei Lin; Yang-Chang Wu
Journal:  Int J Mol Sci       Date:  2021-06-10       Impact factor: 5.923
  5 in total

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