Literature DB >> 23135237

Management of growing vestibular schwannomas.

Gian Gaetano Ferri1, Antonio Pirodda, Alberto Rinaldi Ceroni, Antonio Fioravanti, Fabio Calbucci, Giovanni Carlo Modugno.   

Abstract

Conservative management of small vestibular schwannomas is frequently proposed as most tumours do not grow. Anyway, tumour growth is reported in 30-40 % of the cases, so that surgery is consequently generally proposed. We primarily observed 161 patients affected by unilateral vestibular schwannomas. All patients were examined by means of gadolinium-enhanced magnetic resonance imaging scans. Tumour growth was recorded in 58 cases (35.8 %) and these subjects set up the group of study. Twenty-two (37.9 %) patients were surgically treated; tumour was always completely removed, all patients had normal facial function after surgery and only one patient suffered from a major complication (cerebellar haematoma). Fourteen patients (24.1 %) were submitted to radiotherapy, while one patient was lost at follow-up and another one died because of other medical reasons. Finally, 20 (34.5 %) subjects continued to be observed for different reasons. The mean follow-up period after identification of growth was 6.1 years. Nine tumours continued to grow, nine tumours stopped growing, one tumour grew and then regressed in size and one tumour decreased. Sixty percent of patients with useful hearing at diagnosis preserved it during the entire observation period. In conclusion, most of VS do not grow; in case of tumour growth, a surgical procedure may be suggested and the outcomes are not negatively influenced by the delay of the procedure. But in some cases, patients can still follow the "wait and scan" policy. In fact, only less than half of the growing tumours continued to grow. Moreover, most of the patients continued to retain a useful hearing.

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Year:  2012        PMID: 23135237     DOI: 10.1007/s00405-012-2248-4

Source DB:  PubMed          Journal:  Eur Arch Otorhinolaryngol        ISSN: 0937-4477            Impact factor:   2.503


  33 in total

1.  Conservative management of unilateral acoustic neuromas.

Authors:  D C Tschudi; T E Linder; U Fisch
Journal:  Am J Otol       Date:  2000-09

2.  Long-term hearing preservation in vestibular schwannoma.

Authors:  Sven-Eric Stangerup; Jens Thomsen; Mirko Tos; Per Cayé-Thomasen
Journal:  Otol Neurotol       Date:  2010-02       Impact factor: 2.311

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Authors:  M J Fucci; C A Buchman; D E Brackmann; K I Berliner
Journal:  Am J Otol       Date:  1999-07

4.  Facial nerve function after vestibular schwannoma surgery following failed conservative management.

Authors:  Mikkel Kaltoft; Sven-Eric Stangerup; Per Caye-Thomasen
Journal:  Neurosurgery       Date:  2012-02       Impact factor: 4.654

5.  A large vestibular schwannoma that did not grow for 18 years.

Authors:  F C A Timmer; K Graamans
Journal:  B-ENT       Date:  2011       Impact factor: 0.082

6.  Management of acoustic neuromas in patients 65 years or older.

Authors:  Pamela C Roehm; Bruce J Gantz
Journal:  Otol Neurotol       Date:  2007-08       Impact factor: 2.311

7.  Conservative treatment of patients with acoustic tumors.

Authors:  J B Bederson; K von Ammon; W W Wichmann; M G Yasargil
Journal:  Neurosurgery       Date:  1991-05       Impact factor: 4.654

8.  Conservative management of vestibular schwannomas: an effective strategy.

Authors:  Gian Gaetano Ferri; Giovanni Carlo Modugno; Antonio Pirodda; Antonio Fioravanti; Fabio Calbucci; Alberto Rinaldi Ceroni
Journal:  Laryngoscope       Date:  2008-06       Impact factor: 3.325

9.  Committee on Hearing and Equilibrium guidelines for the evaluation of hearing preservation in acoustic neuroma (vestibular schwannoma). American Academy of Otolaryngology-Head and Neck Surgery Foundation, INC.

Authors: 
Journal:  Otolaryngol Head Neck Surg       Date:  1995-09       Impact factor: 3.497

Review 10.  Distinct spontaneous shrinkage of a sporadic vestibular schwannoma.

Authors:  Xiaowen Huang; Per Caye-Thomasen; Sven-Eric Stangerup
Journal:  Auris Nasus Larynx       Date:  2012-08-01       Impact factor: 1.863

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  2 in total

Review 1.  What is the Required Frequency of MRI Scanning in the Wait and Scan Management?

Authors:  Thomas Somers; Romain Kania; Jerome Waterval; Tony Van Havenbergh
Journal:  J Int Adv Otol       Date:  2018-04       Impact factor: 1.017

2.  Observation or stereotactic radiosurgery for newly diagnosed vestibular schwannomas: A systematic review and meta-analysis.

Authors:  Janet Leon; Eric J Lehrer; Jennifer Peterson; Laura Vallow; Henry Ruiz-Garcia; Austin Hadley; Steven Herchko; Larry Lundy; Kaisorn Chaichana; Prasanna Vibhute; Jason P Sheehan; Daniel M Trifiletti
Journal:  J Radiosurg SBRT       Date:  2019
  2 in total

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