Literature DB >> 23134325

An apparent case of undiagnosed donor Kawasaki disease manifesting as coronary artery aneurysm in a pediatric heart transplant recipient.

Joshua Friedland-Little1, Ranjit Aiyagari, Robert J Gajarski, Kurt R Schumacher.   

Abstract

We present a case of coronary ectasia and LAD coronary artery aneurysm with angiographic characteristics of Kawasaki disease in a three-yr-old girl two-yr status post-orthotopic heart transplant. Coronary anomalies were noted during initial screening coronary angiography two yr after transplant. Subsequent review of the donor echocardiogram revealed that the LMCA had been mildly dilated prior to transplant. In the absence of any symptoms consistent with Kawasaki disease in the transplant recipient, this appears to be a case of Kawasaki disease in the organ donor manifesting with coronary anomalies in the transplant recipient. The patient has done well clinically, and repeat coronary angiography has revealed partial regression of coronary anomalies. Given multiple reports in the literature of persistent abnormalities of coronary artery morphology and function after Kawasaki disease, close monitoring is warranted, with consideration of potential coronary protective medical therapies.
© 2012 John Wiley & Sons A/S.

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Year:  2012        PMID: 23134325     DOI: 10.1111/petr.12014

Source DB:  PubMed          Journal:  Pediatr Transplant        ISSN: 1397-3142


  1 in total

1.  Seasonality of Kawasaki disease: a global perspective.

Authors:  Jane C Burns; Lauren Herzog; Olivia Fabri; Adriana H Tremoulet; Xavier Rodó; Ritei Uehara; David Burgner; Emelia Bainto; David Pierce; Mary Tyree; Daniel Cayan
Journal:  PLoS One       Date:  2013-09-18       Impact factor: 3.240

  1 in total

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