A K Shah1, L S Vohra. 1. Department of Surgery, Armed Forces Medical College, Pune, Maharashtra, India.
Abstract
BACKGROUND: Traditionally outcomes of treatment have been limited to survival. However, the disease and its treatment may have an impact on Quality-of- Life (QoL). The major concerns for patients of carcinoma breast involved are survival, appearance and a fear of recurrence. In Indian society we may need a separate and modified approach to assess QoL. AIMS #ENTITYSTARTX00026; OBJECTIVE: The aim of this study was to assess the QoL of patients of carcinoma breast and to ascertaining pitfalls for suitable correction in future studies on Indian patients. MATERIALS #ENTITYSTARTX00026; METHODS: 250 diagnosed patients of carcinoma breast were studied by a questionnaire on physical and psychological parameters. The results were assessed for applicability to our clientele. RESULTS: We found that majority of patients enjoy a good and non-capacitating QoL. Factors that may contribute to poorer health perceptions and QoL include experiencing a menopausal transition as part of therapy, and feeling more vulnerable after cancer. Overall QoL was better in the older and illiterate patients. Patients with no co morbidity and early stage disease fared better against patients with co morbidities and advanced stage of malignancy. The parameters used in QoL studies in west may not be directly applicable to Indian patients but it does give us a start. We need to adapt to these parameters and draw our conclusion. But there are many methodological challenges inherent in working with our population. Researchers interested in studying our clientele's QoL need to be cognizant of certain issues to ensure high quality results.
BACKGROUND: Traditionally outcomes of treatment have been limited to survival. However, the disease and its treatment may have an impact on Quality-of- Life (QoL). The major concerns for patients of carcinoma breast involved are survival, appearance and a fear of recurrence. In Indian society we may need a separate and modified approach to assess QoL. AIMS #ENTITYSTARTX00026; OBJECTIVE: The aim of this study was to assess the QoL of patients of carcinoma breast and to ascertaining pitfalls for suitable correction in future studies on Indian patients. MATERIALS #ENTITYSTARTX00026; METHODS: 250 diagnosed patients of carcinoma breast were studied by a questionnaire on physical and psychological parameters. The results were assessed for applicability to our clientele. RESULTS: We found that majority of patients enjoy a good and non-capacitating QoL. Factors that may contribute to poorer health perceptions and QoL include experiencing a menopausal transition as part of therapy, and feeling more vulnerable after cancer. Overall QoL was better in the older and illiterate patients. Patients with no co morbidity and early stage disease fared better against patients with co morbidities and advanced stage of malignancy. The parameters used in QoL studies in west may not be directly applicable to Indian patients but it does give us a start. We need to adapt to these parameters and draw our conclusion. But there are many methodological challenges inherent in working with our population. Researchers interested in studying our clientele's QoL need to be cognizant of certain issues to ensure high quality results.
Entities:
Keywords:
Breast cancer; Quality of life; Treatment of breast cancer; survival in breast cancer
Authors: Tim A Ahles; Andrew J Saykin; Charlotte T Furstenberg; Bernard Cole; Leila A Mott; Karen Skalla; Marie B Whedon; Sarah Bivens; Tara Mitchell; E Robert Greenberg; Peter M Silberfarb Journal: J Clin Oncol Date: 2002-01-15 Impact factor: 44.544
Authors: Timothy L Lash; Soe Soe Thwin; Nicholas J Horton; Edward Guadagnoli; Rebecca A Silliman Journal: Am J Epidemiol Date: 2003-02-01 Impact factor: 4.897