Literature DB >> 23132721

Dimebon activates autophagosome components in human neuroblastoma SH-SY5Y cells.

I V Khritankova1, M S Kukharskiy, O A Lytkina, S O Bachurin, B Y Shorning.   

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Year:  2012        PMID： 23132721     DOI： 10.1134/S1607672912050079

Source DB:  PubMed          Journal:  Dokl Biochem Biophys        ISSN： 1607-6729            Impact factor:   0.788


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  11 in total

1.  Hindering of proteinopathy-induced neurodegeneration as a new mechanism of action for neuroprotectors and cognition enhancing compounds.

Authors:  S O Bachurin; A A Ustyugov; O Peters; T A Shelkovnikova; V L Buchman; N N Ninkina
Journal:  Dokl Biochem Biophys       Date:  2009 Sep-Oct       Impact factor: 0.788

2.  Structure of Atg5.Atg16, a complex essential for autophagy.

Authors:  Minako Matsushita; Nobuo N Suzuki; Keisuke Obara; Yuko Fujioka; Yoshinori Ohsumi; Fuyuhiko Inagaki
Journal:  J Biol Chem       Date:  2006-12-27       Impact factor: 5.157

3.  Development of proneurogenic, neuroprotective small molecules.

Authors:  Karen S MacMillan; Jacinth Naidoo; Jue Liang; Lisa Melito; Noelle S Williams; Lorraine Morlock; Paula J Huntington; Sandi Jo Estill; Jamie Longgood; Ginger L Becker; Steven L McKnight; Andrew A Pieper; Jef K De Brabander; Joseph M Ready
Journal:  J Am Chem Soc       Date:  2011-01-06       Impact factor: 15.419

4.  Human IRGM regulates autophagy and cell-autonomous immunity functions through mitochondria.

Authors:  Sudha B Singh; Wojciech Ornatowski; Isabelle Vergne; John Naylor; Monica Delgado; Esteban Roberts; Marisa Ponpuak; Sharon Master; Manohar Pilli; Eileen White; Masaaki Komatsu; Vojo Deretic
Journal:  Nat Cell Biol       Date:  2010-11-21       Impact factor: 28.824

Review 5.  Control of the autophagy maturation step by the MAPK ERK and p38: lessons from environmental carcinogens.

Authors:  Elisabeth Corcelle; Nadir Djerbi; Mireille Mari; Marielle Nebout; Céline Fiorini; Patrick Fénichel; Paul Hofman; Philippe Poujeol; Baharia Mograbi
Journal:  Autophagy       Date:  2007-01-21       Impact factor: 16.016

6.  Dimebon (latrepirdine) enhances mitochondrial function and protects neuronal cells from death.

Authors:  Shouting Zhang; Louise Hedskog; Camilla A Hansson Petersen; Bengt Winblad; Maria Ankarcrona
Journal:  J Alzheimers Dis       Date:  2010       Impact factor: 4.472

7.  Discovery of a proneurogenic, neuroprotective chemical.

Authors:  Andrew A Pieper; Shanhai Xie; Emanuela Capota; Sandi Jo Estill; Jeannie Zhong; Jeffrey M Long; Ginger L Becker; Paula Huntington; Shauna E Goldman; Ching-Han Shen; Maria Capota; Jeremiah K Britt; Tiina Kotti; Kerstin Ure; Daniel J Brat; Noelle S Williams; Karen S MacMillan; Jacinth Naidoo; Lisa Melito; Jenny Hsieh; Jef De Brabander; Joseph M Ready; Steven L McKnight
Journal:  Cell       Date:  2010-07-09       Impact factor: 41.582

8.  Effect of dimebon on cognition, activities of daily living, behaviour, and global function in patients with mild-to-moderate Alzheimer's disease: a randomised, double-blind, placebo-controlled study.

Authors:  Rachelle S Doody; Svetlana I Gavrilova; Mary Sano; Ronald G Thomas; Paul S Aisen; Sergey O Bachurin; Lynn Seely; David Hung
Journal:  Lancet       Date:  2008-07-19       Impact factor: 79.321

9.  Dimebon slows progression of proteinopathy in γ-synuclein transgenic mice.

Authors:  Sergey O Bachurin; Tatyana A Shelkovnikova; Alexey A Ustyugov; Owen Peters; Ina Khritankova; Marina A Afanasieva; Tatyana V Tarasova; Igor I Alentov; Vladimir L Buchman; Natalia N Ninkina
Journal:  Neurotox Res       Date:  2011-12-17       Impact factor: 3.911

10.  Regulation of autophagy by kinases.

Authors:  Savitha Sridharan; Kirti Jain; Alakananda Basu
Journal:  Cancers (Basel)       Date:  2011-06-09       Impact factor: 6.639
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  6 in total

Review 1.  Novel Sites of Neuroprotective Action of Dimebon (Latrepirdine).

Authors:  Aleksey Ustyugov; Elena Shevtsova; Sergey Bachurin
Journal:  Mol Neurobiol       Date:  2015-06-30       Impact factor: 5.590

Review 2.  Mitochondrial Pharmacology of Dimebon (Latrepirdine) Calls for a New Look at its Possible Therapeutic Potential in Alzheimer's Disease.

Authors:  Schamim H Eckert; Janett Gaca; Nathalie Kolesova; Kristina Friedland; Gunter P Eckert; Walter E Muller
Journal:  Aging Dis       Date:  2018-08-01       Impact factor: 6.745

3.  Gamma-Carbolines Derivatives As Promising Agents for the Development of Pathogenic Therapy for Proteinopathy.

Authors:  V I Skvortsova; S O Bachurin; A A Ustyugov; M S Kukharsky; A V Deikin; V L Buchman; N N Ninkina
Journal:  Acta Naturae       Date:  2018 Oct-Dec       Impact factor: 1.845

4.  Distinct TP53 Mutation Types Exhibit Increased Sensitivity to Ferroptosis Independently of Changes in Iron Regulatory Protein Activity.

Authors:  Laurie R Thompson; Thais G Oliveira; Evan R Hermann; Winyoo Chowanadisai; Stephen L Clarke; McKale R Montgomery
Journal:  Int J Mol Sci       Date:  2020-09-15       Impact factor: 5.923

5.  A bioisostere of Dimebon/Latrepirdine delays the onset and slows the progression of pathology in FUS transgenic mice.

Authors:  Kirill Chaprov; Alexander Rezvykh; Sergei Funikov; Tamara A Ivanova; Ekaterina A Lysikova; Alexei V Deykin; Michail S Kukharsky; Alexey Yu Aksinenko; Sergey O Bachurin; Natalia Ninkina; Vladimir L Buchman
Journal:  CNS Neurosci Ther       Date:  2021-03-23       Impact factor: 5.243

6.  The Effects of Latrepirdine on Amyloid-β Aggregation and Toxicity.

Authors:  Tenielle Porter; Prashant Bharadwaj; David Groth; Adrian Paxman; Simon M Laws; Ralph N Martins; Giuseppe Verdile
Journal:  J Alzheimers Dis       Date:  2016       Impact factor: 4.472
  6 in total

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