| Literature DB >> 23132505 |
Sylvain Brohée1, Gianluca Bontempi.
Abstract
ChIP-sequencing is a method of choice to localize the positions of protein binding sites on DNA on a whole genomic scale. The deciphering of the sequencing data produced by this novel technique is challenging and it is achieved by their rigorous interpretation using dedicated tools and adapted visualization programs. Here, we present a bioinformatics tool (D-peaks) that adds several possibilities (including, user-friendliness, high-quality, relative position with respect to the genomic features) to the well-known visualization browsers or databases already existing. D-peaks is directly available through its web interface http://rsat.ulb.ac.be/dpeaks/ as well as a command line tool.Entities:
Keywords: ChIPseq; bioinformatics; high-throughput sequencing; transcription factor; visualization
Mesh:
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Year: 2012 PMID: 23132505 PMCID: PMC3632623 DOI: 10.4161/trns.22457
Source DB: PubMed Journal: Transcription ISSN: 2154-1272