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Literature DB >> 23131919

Setting Snail2's pace during EMT.

Haritha Mathsyaraja¹, Michael C Ostrowski.

Abstract

Epithelial to mesenchymal transition (EMT) is a fundamental process in both development and cancer progression. The transcription factor Elf5 is now reported as an upstream regulator of the key EMT inducer Snail2, and is shown to regulate the earliest known rewiring events required for tumour cell invasiveness and metastasis.

Entities: Disease Gene

Mesh：

Substances：

Year: 2012 PMID： 23131919 DOI： 10.1038/ncb2616

Source DB: PubMed Journal: Nat Cell Biol ISSN： 1465-7392 Impact factor: 28.824

15 in total

Review 1. The Elf group of Ets-related transcription factors. ELF3 and ELF5.

Authors: R S Thomas; A N Ng; J Zhou; M J Tymms; W Doppler; I Kola
Journal: Adv Exp Med Biol Date: 2000 Impact factor: 2.622

Review 2. Snail, Zeb and bHLH factors in tumour progression: an alliance against the epithelial phenotype?

Authors: Héctor Peinado; David Olmeda; Amparo Cano
Journal: Nat Rev Cancer Date: 2007-05-17 Impact factor: 60.716

Review 3. Epithelial-mesenchymal transition: at the crossroads of development and tumor metastasis.

Authors: Jing Yang; Robert A Weinberg
Journal: Dev Cell Date: 2008-06 Impact factor: 12.270

Review 4. Epithelial-mesenchymal transitions in development and disease.

Authors: Jean Paul Thiery; Hervé Acloque; Ruby Y J Huang; M Angela Nieto
Journal: Cell Date: 2009-11-25 Impact factor: 41.582

5. Lineage specific methylation of the Elf5 promoter in mammary epithelial cells.

Authors: Heather J Lee; Rebecca A Hinshelwood; Toula Bouras; David Gallego-Ortega; Fátima Valdés-Mora; Katrina Blazek; Jane E Visvader; Susan J Clark; Christopher J Ormandy
Journal: Stem Cells Date: 2011-10 Impact factor: 6.277

6. Elf5 regulates mammary gland stem/progenitor cell fate by influencing notch signaling.

Authors: Rumela Chakrabarti; Yong Wei; Rose-Anne Romano; Christina DeCoste; Yibin Kang; Satrajit Sinha
Journal: Stem Cells Date: 2012-07 Impact factor: 6.277

7. Pten in stromal fibroblasts suppresses mammary epithelial tumours.

Authors: Anthony J Trimboli; Carmen Z Cantemir-Stone; Fu Li; Julie A Wallace; Anand Merchant; Nicholas Creasap; John C Thompson; Enrico Caserta; Hui Wang; Jean-Leon Chong; Shan Naidu; Guo Wei; Sudarshana M Sharma; Julie A Stephens; Soledad A Fernandez; Metin N Gurcan; Michael B Weinstein; Sanford H Barsky; Lisa Yee; Thomas J Rosol; Paul C Stromberg; Michael L Robinson; Francois Pepin; Michael Hallett; Morag Park; Michael C Ostrowski; Gustavo Leone
Journal: Nature Date: 2009-10-22 Impact factor: 49.962

Review 8. Microenvironmental regulation of metastasis.

Authors: Johanna A Joyce; Jeffrey W Pollard
Journal: Nat Rev Cancer Date: 2008-03-12 Impact factor: 60.716

9. Reprogramming of the tumour microenvironment by stromal PTEN-regulated miR-320.

Authors: A Bronisz; J Godlewski; J A Wallace; A S Merchant; M O Nowicki; H Mathsyaraja; R Srinivasan; A J Trimboli; C K Martin; F Li; L Yu; S A Fernandez; T Pécot; T J Rosol; S Cory; M Hallett; M Park; M G Piper; C B Marsh; L D Yee; R E Jimenez; G Nuovo; S E Lawler; E A Chiocca; G Leone; M C Ostrowski
Journal: Nat Cell Biol Date: 2011-12-18 Impact factor: 28.824

10. Elf5 inhibits the epithelial-mesenchymal transition in mammary gland development and breast cancer metastasis by transcriptionally repressing Snail2.

Authors: Rumela Chakrabarti; Julie Hwang; Mario Andres Blanco; Yong Wei; Martin Lukačišin; Rose-Anne Romano; Kirsten Smalley; Song Liu; Qifeng Yang; Toni Ibrahim; Laura Mercatali; Dino Amadori; Bruce G Haffty; Satrajit Sinha; Yibin Kang
Journal: Nat Cell Biol Date: 2012-10-21 Impact factor: 28.824

4 in total