Literature DB >> 23131853

rAAV-mediated tumorigenesis: still unresolved after an AAV assault.

Paul N Valdmanis1, Leszek Lisowski, Mark A Kay.   

Abstract

Mesh:

Year:  2012        PMID: 23131853      PMCID: PMC3498811          DOI: 10.1038/mt.2012.220

Source DB:  PubMed          Journal:  Mol Ther        ISSN: 1525-0016            Impact factor:   11.454


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  26 in total

1.  Extrachromosomal recombinant adeno-associated virus vector genomes are primarily responsible for stable liver transduction in vivo.

Authors:  H Nakai; S R Yant; T A Storm; S Fuess; L Meuse; M A Kay
Journal:  J Virol       Date:  2001-08       Impact factor: 5.103

2.  Mutational activation of the c-Ha-ras gene in liver tumors of different rodent strains: correlation with susceptibility to hepatocarcinogenesis.

Authors:  A Buchmann; R Bauer-Hofmann; J Mahr; N R Drinkwater; A Luz; M Schwarz
Journal:  Proc Natl Acad Sci U S A       Date:  1991-02-01       Impact factor: 11.205

3.  No evidence for tumorigenesis of AAV vectors in a large-scale study in mice.

Authors:  Peter Bell; Lili Wang; Corinna Lebherz; Douglas B Flieder; Mark S Bove; Di Wu; Guang Ping Gao; James M Wilson; Nelson A Wivel
Journal:  Mol Ther       Date:  2005-08       Impact factor: 11.454

4.  Large-scale molecular characterization of adeno-associated virus vector integration in mouse liver.

Authors:  Hiroyuki Nakai; Xiaolin Wu; Sally Fuess; Theresa A Storm; David Munroe; Eugenio Montini; Shawn M Burgess; Markus Grompe; Mark A Kay
Journal:  J Virol       Date:  2005-03       Impact factor: 5.103

5.  Observed incidence of tumorigenesis in long-term rodent studies of rAAV vectors.

Authors:  A Donsante; C Vogler; N Muzyczka; J M Crawford; J Barker; T Flotte; M Campbell-Thompson; T Daly; M S Sands
Journal:  Gene Ther       Date:  2001-09       Impact factor: 5.250

6.  DNA-PKcs: a T-cell tumour suppressor encoded at the mouse scid locus.

Authors:  C Jhappan; H C Morse; R D Fleischmann; M M Gottesman; G Merlino
Journal:  Nat Genet       Date:  1997-12       Impact factor: 38.330

7.  Large-scale analysis of adeno-associated virus vector integration sites in normal human cells.

Authors:  Daniel G Miller; Grant D Trobridge; Lisa M Petek; Michael A Jacobs; Rajinder Kaul; David W Russell
Journal:  J Virol       Date:  2005-09       Impact factor: 5.103

8.  DNA-dependent PK inhibits adeno-associated virus DNA integration.

Authors:  Sihong Song; Yuanqing Lu; Young-Kook Choi; Yinong Han; Qiushi Tang; Ge Zhao; Kenneth I Berns; Terence R Flotte
Journal:  Proc Natl Acad Sci U S A       Date:  2004-02-06       Impact factor: 11.205

9.  High incidence of spontaneous hepatomas and the increase of this incidence with urethan in C3H, C3Hf, and C3He male mice.

Authors:  W E HESTON; G VLAHAKIS; M K DERINGER
Journal:  J Natl Cancer Inst       Date:  1960-02       Impact factor: 13.506

10.  Genetic control of hepatocarcinogenesis in C57BL/6J and C3H/HeJ inbred mice.

Authors:  N R Drinkwater; J J Ginsler
Journal:  Carcinogenesis       Date:  1986-10       Impact factor: 4.944

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  15 in total

1.  Hitting the target without pulling the trigger.

Authors:  Thierry VandenDriessche; Marinee K Chuah
Journal:  Mol Ther       Date:  2015-01       Impact factor: 11.454

2.  Short DNA Hairpins Compromise Recombinant Adeno-Associated Virus Genome Homogeneity.

Authors:  Jun Xie; Qin Mao; Phillip W L Tai; Ran He; Jianzhong Ai; Qin Su; Ye Zhu; Hong Ma; Jia Li; Shoufang Gong; Dan Wang; Zhen Gao; Mengxin Li; Li Zhong; Heather Zhou; Guangping Gao
Journal:  Mol Ther       Date:  2017-04-24       Impact factor: 11.454

Review 3.  Gene regulation and genetics in neurochemistry, past to future.

Authors:  Steven W Barger
Journal:  J Neurochem       Date:  2016-10-17       Impact factor: 5.372

Review 4.  Progress and challenges of gene therapy for Pompe disease.

Authors:  Giuseppe Ronzitti; Fanny Collaud; Pascal Laforet; Federico Mingozzi
Journal:  Ann Transl Med       Date:  2019-07

5.  AAV Infection: Protection from Cancer.

Authors:  Arun Srivastava; Barrie J Carter
Journal:  Hum Gene Ther       Date:  2016-11-10       Impact factor: 5.695

6.  Vector design influences hepatic genotoxicity after adeno-associated virus gene therapy.

Authors:  Randy J Chandler; Matthew C LaFave; Gaurav K Varshney; Niraj S Trivedi; Nuria Carrillo-Carrasco; Julien S Senac; Weiwei Wu; Victoria Hoffmann; Abdel G Elkahloun; Shawn M Burgess; Charles P Venditti
Journal:  J Clin Invest       Date:  2015-01-20       Impact factor: 14.808

Review 7.  Adeno-associated viral vector-mediated immune responses: Understanding barriers to gene delivery.

Authors:  Natalie F Nidetz; Michael C McGee; Longping V Tse; Chengwen Li; Le Cong; Yunxing Li; Weishan Huang
Journal:  Pharmacol Ther       Date:  2019-12-11       Impact factor: 12.310

8.  A Simple, Two-Step, Small-Scale Purification of Recombinant Adeno-Associated Viruses.

Authors:  Shih-Heng Chen; Amy Papaneri; Mitzie Walker; Erica Scappini; Robert D Keys; Negin P Martin
Journal:  J Virol Methods       Date:  2020-05-01       Impact factor: 2.014

Review 9.  Emerging Issues in AAV-Mediated In Vivo Gene Therapy.

Authors:  Pasqualina Colella; Giuseppe Ronzitti; Federico Mingozzi
Journal:  Mol Ther Methods Clin Dev       Date:  2017-12-01       Impact factor: 6.698

10.  A brain microvasculature endothelial cell-specific viral vector with the potential to treat neurovascular and neurological diseases.

Authors:  Jakob Körbelin; Godwin Dogbevia; Stefan Michelfelder; Dirk A Ridder; Agnes Hunger; Jan Wenzel; Henning Seismann; Melanie Lampe; Jacqueline Bannach; Manolis Pasparakis; Jürgen A Kleinschmidt; Markus Schwaninger; Martin Trepel
Journal:  EMBO Mol Med       Date:  2016-06-01       Impact factor: 12.137

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