Literature DB >> 23131668

How to stop: the mysterious links among RNA polymerase II occupancy 3' of genes, mRNA 3' processing and termination.

Krishanpal Anamika1, Àkos Gyenis, Laszlo Tora.   

Abstract

Eukaryotic genes are transcribed by RNA polymerase II (RNAP II) through cycles of initiation, elongation and termination. Termination remains the least understood stage of transcription. Here we discuss the role of RNAP II occupancy downstream of the 3'ends of genes and its links with termination and mRNA 3' processing.

Keywords:  End of Annotated Gene; RNA Polymerase II pause; core histone genes; genome-wide mapping; polyadenylation; transcription termination

Mesh：

Substances：

Year:  2012        PMID： 23131668      PMCID： PMC3644043          DOI： 10.4161/trns.22300

Source DB:  PubMed          Journal:  Transcription        ISSN： 2154-1272


  36 in total

1.  Specific transcriptional pausing activates polyadenylation in a coupled in vitro system.

Authors:  M Yonaha; N J Proudfoot
Journal:  Mol Cell       Date:  1999-05       Impact factor: 17.970

2.  Terminal exon definition occurs cotranscriptionally and promotes termination of RNA polymerase II.

Authors:  M J Dye; N J Proudfoot
Journal:  Mol Cell       Date:  1999-03       Impact factor: 17.970

3.  The poly(A) signal, without the assistance of any downstream element, directs RNA polymerase II to pause in vivo and then to release stochastically from the template.

Authors:  Ian J Orozco; Steven J Kim; Harold G Martinson
Journal:  J Biol Chem       Date:  2002-08-23       Impact factor: 5.157

4.  Poly(A)-dependent transcription termination: continued communication of the poly(A) signal with the polymerase is required long after extrusion in vivo.

Authors:  Steven J Kim; Harold G Martinson
Journal:  J Biol Chem       Date:  2003-08-21       Impact factor: 5.157

Review 5.  Connections between mRNA 3' end processing and transcription termination.

Authors:  Stephen Buratowski
Journal:  Curr Opin Cell Biol       Date:  2005-06       Impact factor: 8.382

6.  The role of Rat1 in coupling mRNA 3'-end processing to transcription termination: implications for a unified allosteric-torpedo model.

Authors:  Weifei Luo; Arlen W Johnson; David L Bentley
Journal:  Genes Dev       Date:  2006-04-05       Impact factor: 11.361

Review 7.  Multilevel regulation of replication-dependent histone genes.

Authors:  D Schümperli
Journal:  Trends Genet       Date:  1988-07       Impact factor: 11.639

8.  Compensatory mutations suggest that base-pairing with a small nuclear RNA is required to form the 3' end of H3 messenger RNA.

Authors:  F Schaufele; G M Gilmartin; W Bannwarth; M L Birnstiel
Journal:  Nature       Date:  1986 Oct 30-Nov 5       Impact factor: 49.962

Review 9.  Formation of the 3' end of histone mRNA.

Authors:  Z Dominski; W F Marzluff
Journal:  Gene       Date:  1999-10-18       Impact factor: 3.688

10.  Dynamic transitions in RNA polymerase II density profiles during transcription termination.

Authors:  Ana Rita Grosso; Sérgio Fernandes de Almeida; José Braga; Maria Carmo-Fonseca
Journal:  Genome Res       Date:  2012-06-08       Impact factor: 9.043
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  7 in total

1.  Effects of Transcription Elongation Rate and Xrn2 Exonuclease Activity on RNA Polymerase II Termination Suggest Widespread Kinetic Competition.

Authors:  Nova Fong; Kristopher Brannan; Benjamin Erickson; Hyunmin Kim; Michael A Cortazar; Ryan M Sheridan; Tram Nguyen; Shai Karp; David L Bentley
Journal:  Mol Cell       Date:  2015-10-15       Impact factor: 17.970

2.  The 3' Pol II pausing at replication-dependent histone genes is regulated by Mediator through Cajal bodies' association with histone locus bodies.

Authors:  Hidefumi Suzuki; Ryota Abe; Miho Shimada; Tomonori Hirose; Hiroko Hirose; Keisuke Noguchi; Yoko Ike; Nanami Yasui; Kazuki Furugori; Yuki Yamaguchi; Atsushi Toyoda; Yutaka Suzuki; Tatsuro Yamamoto; Noriko Saitoh; Shigeo Sato; Chieri Tomomori-Sato; Ronald C Conaway; Joan W Conaway; Hidehisa Takahashi
Journal:  Nat Commun       Date:  2022-05-25       Impact factor: 17.694

3.  An Annotation Agnostic Algorithm for Detecting Nascent RNA Transcripts in GRO-Seq.

Authors:  Joseph G Azofeifa; Mary A Allen; Manuel E Lladser; Robin D Dowell
Journal:  IEEE/ACM Trans Comput Biol Bioinform       Date:  2016-01-26       Impact factor: 3.710

4.  Heat Shock Causes a Reversible Increase in RNA Polymerase II Occupancy Downstream of mRNA Genes, Consistent with a Global Loss in Transcriptional Termination.

Authors:  Joseph F Cardiello; James A Goodrich; Jennifer F Kugel
Journal:  Mol Cell Biol       Date:  2018-08-28       Impact factor: 4.272

5.  Runaway transcription.

Authors:  Jiannan Guo; Tiandao Li; David H Price
Journal:  Genome Biol       Date:  2013       Impact factor: 13.583

6.  UVB induces a genome-wide acting negative regulatory mechanism that operates at the level of transcription initiation in human cells.

Authors:  Akos Gyenis; David Umlauf; Zsuzsanna Ujfaludi; Imre Boros; Tao Ye; Làszlò Tora
Journal:  PLoS Genet       Date:  2014-07-24       Impact factor: 5.917

7.  A single-molecule view of transcription reveals convoys of RNA polymerases and multi-scale bursting.

Authors:  Katjana Tantale; Florian Mueller; Alja Kozulic-Pirher; Annick Lesne; Jean-Marc Victor; Marie-Cécile Robert; Serena Capozi; Racha Chouaib; Volker Bäcker; Julio Mateos-Langerak; Xavier Darzacq; Christophe Zimmer; Eugenia Basyuk; Edouard Bertrand
Journal:  Nat Commun       Date:  2016-07-27       Impact factor: 14.919
  7 in total

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