Literature DB >> 23131665

The role of epigenetic transcriptional regulation in BRCA1-mediated tumor suppression.

Suhwan Chang1, Shyam K Sharan.   

Abstract

Mutation in BRCA1 accounts for half of all familial breast cancer cases. Recent studies have shown its role in the epigenetic regulation of an oncogenic microRNA, revealing a novel mode of tumor suppression that is independent of its well-established role in DNA repair and cell cycle regulation.

Entities:  

Keywords:  BRCA1; breast cancer; epigenetic regulation; miR-155; micro RNA; transcription

Mesh：

Substances：

Year:  2012        PMID： 23131665      PMCID： PMC3644038          DOI： 10.4161/trns.22600

Source DB:  PubMed          Journal:  Transcription        ISSN： 2154-1272


  39 in total

1.  BRCA1 interacts with components of the histone deacetylase complex.

Authors:  R I Yarden; L C Brody
Journal:  Proc Natl Acad Sci U S A       Date:  1999-04-27       Impact factor: 11.205

2.  Binding and recognition in the assembly of an active BRCA1/BARD1 ubiquitin-ligase complex.

Authors:  Peter S Brzovic; Jennifer R Keeffe; Hiroyuki Nishikawa; Keiko Miyamoto; David Fox; Mamoru Fukuda; Tomohiko Ohta; Rachel Klevit
Journal:  Proc Natl Acad Sci U S A       Date:  2003-05-05       Impact factor: 11.205

3.  bic, a novel gene activated by proviral insertions in avian leukosis virus-induced lymphomas, is likely to function through its noncoding RNA.

Authors:  W Tam; D Ben-Yehuda; W S Hayward
Journal:  Mol Cell Biol       Date:  1997-03       Impact factor: 4.272

4.  Identification of a RING protein that can interact in vivo with the BRCA1 gene product.

Authors:  L C Wu; Z W Wang; J T Tsan; M A Spillman; A Phung; X L Xu; M C Yang; L Y Hwang; A M Bowcock; R Baer
Journal:  Nat Genet       Date:  1996-12       Impact factor: 38.330

5.  Pre-B cell proliferation and lymphoblastic leukemia/high-grade lymphoma in E(mu)-miR155 transgenic mice.

Authors:  Stefan Costinean; Nicola Zanesi; Yuri Pekarsky; Esmerina Tili; Stefano Volinia; Nyla Heerema; Carlo M Croce
Journal:  Proc Natl Acad Sci U S A       Date:  2006-04-25       Impact factor: 11.205

6.  Structure and mechanism of BRCA1 BRCT domain recognition of phosphorylated BACH1 with implications for cancer.

Authors:  Julie A Clapperton; Isaac A Manke; Drew M Lowery; Timmy Ho; Lesley F Haire; Michael B Yaffe; Stephen J Smerdon
Journal:  Nat Struct Mol Biol       Date:  2004-05-09       Impact factor: 15.369

Review 7.  miR-155: on the crosstalk between inflammation and cancer.

Authors:  Esmerina Tili; Carlo M Croce; Jean-Jacques Michaille
Journal:  Int Rev Immunol       Date:  2009       Impact factor: 5.311

8.  BRCA1 and c-Myc associate to transcriptionally repress psoriasin, a DNA damage-inducible gene.

Authors:  Richard D Kennedy; Julia J Gorski; Jennifer E Quinn; Gail E Stewart; Colin R James; Stephen Moore; Karl Mulligan; Ethan D Emberley; Tong F Lioe; Patrick J Morrison; Paul B Mullan; George Reid; Patrick G Johnston; Peter H Watson; D Paul Harkin
Journal:  Cancer Res       Date:  2005-11-15       Impact factor: 12.701

9.  The ubiquitin E3 ligase activity of BRCA1 and its biological functions.

Authors:  Wenwen Wu; Ayaka Koike; Takashi Takeshita; Tomohiko Ohta
Journal:  Cell Div       Date:  2008-01-07       Impact factor: 5.130

10.  Concerted transcriptional regulation by BRCA1 and COBRA1 in breast cancer cells.

Authors:  Sarah E Aiyar; HyungJun Cho; Jae Lee; Rong Li
Journal:  Int J Biol Sci       Date:  2007-11-26       Impact factor: 6.580
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  7 in total

1.  MiR-300 regulate the malignancy of breast cancer by targeting p53.

Authors:  Xiao-Heng Xu; Da-Wei Li; Hui Feng; Hong-Mei Chen; Yan-Qiu Song
Journal:  Int J Clin Exp Med       Date:  2015-05-15

2.  MiR-578 and miR-573 as potential players in BRCA-related breast cancer angiogenesis.

Authors:  Katia Danza; Simona De Summa; Rosamaria Pinto; Brunella Pilato; Orazio Palumbo; Giuseppe Merla; Gianni Simone; Stefania Tommasi
Journal:  Oncotarget       Date:  2015-01-01

3.  A portable BRCA1-HAC (human artificial chromosome) module for analysis of BRCA1 tumor suppressor function.

Authors:  Artem V Kononenko; Ruchi Bansal; Nicholas C O Lee; Brenda R Grimes; Hiroshi Masumoto; William C Earnshaw; Vladimir Larionov; Natalay Kouprina
Journal:  Nucleic Acids Res       Date:  2014-09-26       Impact factor: 16.971

4.  BRCA1-associated R-loop affects transcription and differentiation in breast luminal epithelial cells.

Authors:  Huai-Chin Chiang; Xiaowen Zhang; Jingwei Li; Xiayan Zhao; Jerry Chen; Howard T-H Wang; Ismail Jatoi; Andrew Brenner; Yanfen Hu; Rong Li
Journal:  Nucleic Acids Res       Date:  2019-06-04       Impact factor: 16.971

5.  BRCA1 regulates the cancer stem cell fate of breast cancer cells in the context of hypoxia and histone deacetylase inhibitors.

Authors:  Hoon Kim; Qun Lin; Zhong Yun
Journal:  Sci Rep       Date:  2019-07-04       Impact factor: 4.379

6.  Mitochondrial fission determines cisplatin sensitivity in tongue squamous cell carcinoma through the BRCA1-miR-593-5p-MFF axis.

Authors:  Song Fan; Bodu Liu; Lijuan Sun; Xiao-bin Lv; Zhaoyu Lin; Weixiong Chen; Weiliang Chen; Qionglan Tang; Youyuan Wang; Yuxiong Su; Shaowen Jin; Daming Zhang; Jianglong Zhong; Yilin Li; Bin Wen; Zhang Zhang; Pu Yang; Bin Zhou; Qixiang Liang; Xing Yu; Yinghua Zhu; Pengnan Hu; Junjun Chu; Wei Huang; Yuhuan Feng; Hongzhuang Peng; Qihong Huang; Erwei Song; Jinsong Li
Journal:  Oncotarget       Date:  2015-06-20

7.  Integrative Bioinformatics and Functional Analyses of GEO, ENCODE, and TCGA Reveal FADD as a Direct Target of the Tumor Suppressor BRCA1.

Authors:  Dinh-Duc Nguyen; Dong Gyu Lee; Sinae Kim; Keunsoo Kang; Je-Keun Rhee; Suhwan Chang
Journal:  Int J Mol Sci       Date:  2018-05-14       Impact factor: 5.923
  7 in total

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