Literature DB >> 23128805

Alcohol withdrawal.

Anton Manasco1, Shannon Chang, Joseph Larriviere, L Lee Hamm, Marcia Glass.   

Abstract

Alcohol withdrawal is a common clinical condition that has a variety of complications and morbidities. The manifestations can range from mild agitation to withdrawal seizures and delirium tremens. The treatments for alcohol withdrawal include benzodiazepines, anticonvulsants, beta-blockers and antihypertensives. Although benzodiazepines are presently a first-line therapy, there is controversy regarding the efficacies of these medications compared with others. Treatment protocols often involve one of two contrasting approaches: symptom-triggered versus fixed-schedule dosing of benzodiazepines. We describe these protocols in our review and examine the data supporting symptom-triggered dosing as the preferred method for most patients in withdrawal.The Clinical Institute Withdrawal Assessment for Alcohol scoring system for alcohol withdrawal streamlines care, optimizes patient management, and is the best scale available for withdrawal assessment. Quality improvement implications for inpatient management of alcohol withdrawal include increasing training for signs of withdrawal and symptom recognition, adding new hospital protocols to employee curricula, and ensuring manageable patient-to-physician and patient-to-nurse ratios.

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Year:  2012        PMID: 23128805     DOI: 10.1097/SMJ.0b013e31826efb2d

Source DB:  PubMed          Journal:  South Med J        ISSN: 0038-4348            Impact factor:   0.954


  6 in total

1.  Evaluation of mifepristone effects on alcohol-seeking and self-administration in baboons.

Authors:  August F Holtyn; Elise M Weerts
Journal:  Exp Clin Psychopharmacol       Date:  2018-12-20       Impact factor: 3.157

2.  Involvement of delta opioid receptors in alcohol withdrawal-induced mechanical allodynia in male C57BL/6 mice.

Authors:  Doungkamol Alongkronrusmee; Terrance Chiang; Richard M van Rijn
Journal:  Drug Alcohol Depend       Date:  2016-08-21       Impact factor: 4.492

3.  Drug effects on multiple and concurrent schedules of ethanol- and food-maintained behaviour: context-dependent selectivity.

Authors:  B C Ginsburg; R J Lamb
Journal:  Br J Pharmacol       Date:  2014-07       Impact factor: 8.739

4.  Alcohol withdrawal is associated with poorer outcome in acute ischemic stroke.

Authors:  Emmanuel O Akano; Fadar Oliver Otite; Seemant Chaturvedi
Journal:  Neurology       Date:  2019-10-25       Impact factor: 9.910

Review 5.  Dexmedetomidine for the treatment of alcohol withdrawal syndrome: rationale and current status of research.

Authors:  Andrew J Muzyk; Suzanne Kerns; Scott Brudney; Jane P Gagliardi
Journal:  CNS Drugs       Date:  2013-11       Impact factor: 5.749

Review 6.  Alcohol withdrawal syndrome: mechanisms, manifestations, and management.

Authors:  S Jesse; G Bråthen; M Ferrara; M Keindl; E Ben-Menachem; R Tanasescu; E Brodtkorb; M Hillbom; M A Leone; A C Ludolph
Journal:  Acta Neurol Scand       Date:  2016-09-01       Impact factor: 3.209

  6 in total

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