| Literature DB >> 23128289 |
André L P de Abreu1, Paula R B Nogara, Raquel P Souza, Mariana C da Silva, Nelson S Uchimura, Rodrigo L Zanko, Erika C Ferreira, Maria C B Tognim, Jorge J V Teixeira, Fabrícia Gimenes, Marcia E L Consolaro.
Abstract
The question of whether Chlamydia trachomatis (Ct) is a cofactor for human Papillomavirus (HPV) in cervical carcinogenesis is still controversial. We conducted a molecular detection study of both infections in 622 Brazilian women, including 252 women with different grades of abnormal cervical cytology and cervical cancer (CC; cases) and 370 women with normal cytology (controls). Although Ct infection did not seem related to CC carcinogenicity, women with abnormal cytology had a significant high rate of Ct infection. Therefore, it is important to adopt protocols for diagnosis and treatment of this bacterium in conjunction with screening for CC in this population.Entities:
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Year: 2012 PMID: 23128289 PMCID: PMC3516091 DOI: 10.4269/ajtmh.2012.12-0287
Source DB: PubMed Journal: Am J Trop Med Hyg ISSN: 0002-9637 Impact factor: 2.345