Literature DB >> 23127642

Experimental mechanical characterization of abdominal organs: liver, kidney & spleen.

Sagar Umale1, Caroline Deck, Nicolas Bourdet, Parag Dhumane, Luc Soler, Jacques Marescaux, Remy Willinger.   

Abstract

Abdominal organs are the most vulnerable body parts during vehicle trauma, leading to high mortality rate due to acute injuries of liver, kidney, spleen and other abdominal organs. Accurate mechanical properties and FE models of these organs are required for simulating the traumas, so that better designing of the accident environment can be done and the organs can be protected from severe damage. Also from biomedical aspect, accurate mechanical properties of organs are required for better designing of surgical tools and virtual surgery environments. In this study porcine liver, kidney and spleen tissues are studied in vitro and hyper-elastic material laws are provided for each. 12 porcine kidneys are used to perform 40 elongation tests on renal capsule and 60 compression tests on renal cortex, 5 porcine livers are used to perform 45 static compression tests on liver parenchyma and 5 porcine spleens are used to carry out 20 compression tests. All the tests are carried out at a static speed of 0.05 mm/s. A comparative analysis of all the results is done with the literature and though the results are of same order of magnitude, a slight dissonance is observed for the renal capsule. It is also observed that the spleen is the least stiff organ in the abdomen whereas the kidney is the stiffest. The results of this study would be essential to develop the FE models of liver, kidney and spleen which can be further used for impact biomechanical and biomedical applications.
Copyright © 2012 Elsevier Ltd. All rights reserved.

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Year:  2012        PMID: 23127642     DOI: 10.1016/j.jmbbm.2012.07.010

Source DB:  PubMed          Journal:  J Mech Behav Biomed Mater        ISSN: 1878-0180


  18 in total

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2.  Elasticity mapping of murine abdominal organs in vivo using harmonic motion imaging (HMI).

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Journal:  Phys Med Biol       Date:  2016-07-12       Impact factor: 3.609

3.  A continuum thermomechanical model of in vivo electrosurgical heating of hydrated soft biological tissues.

Authors:  Wafaa Karaki; Carlos A Lopez; Diana-Andra Borca-Tasciuc; Suvranu De
Journal:  Int J Heat Mass Transf       Date:  2018-07-14       Impact factor: 5.584

4.  Smoothed particle hydrodynamics simulation of biphasic soft tissue and its medical applications.

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Journal:  Med Biol Eng Comput       Date:  2021-01-08       Impact factor: 2.602

5.  Development of Capsular Fibrosis Beneath the Liver Surface in Humans and Mice.

Authors:  Steven Balog; Yuchang Li; Tomohiro Ogawa; Toshio Miki; Takeshi Saito; Samuel W French; Kinji Asahina
Journal:  Hepatology       Date:  2019-08-27       Impact factor: 17.425

6.  Biomechanical analysis of traumatic mesenteric avulsion.

Authors:  Thierry Bège; Jérémie Ménard; Jaelle Tremblay; Ronald Denis; Pierre-Jean Arnoux; Yvan Petit
Journal:  Med Biol Eng Comput       Date:  2014-11-19       Impact factor: 2.602

7.  Quantitative Analysis of Tissue Damage Evolution in Porcine Liver With Interrupted Mechanical Testing Under Tension, Compression, and Shear.

Authors:  Joseph Chen; Bryn Brazile; Raj Prabhu; Sourav S Patnaik; Robbin Bertucci; Hongjoo Rhee; M F Horstemeyer; Yi Hong; Lakiesha N Williams; Jun Liao
Journal:  J Biomech Eng       Date:  2018-07-01       Impact factor: 2.097

8.  Magnetic Spiderman, a New Surgical Training Device: Study of Safety and Educational Value in a Liver Transplantation Surgical Training Program.

Authors:  Yue Wang; Huan Chen; Bo Tang; Tao Ma; Qingshan Li; Haoyang Zhu; Xiaogang Zhang; Yi Lv; Dinghui Dong
Journal:  World J Surg       Date:  2020-04       Impact factor: 3.352

9.  Characterizing poroelasticity of biological tissues by spherical indentation: an improved theory for large relaxation.

Authors:  Ming Wang; Shaobao Liu; Zhimin Xu; Kai Qu; Moxiao Li; Xin Chen; Qing Xue; Guy M Genin; Tian Jian Lu; Feng Xu
Journal:  J Mech Phys Solids       Date:  2020-03-03       Impact factor: 5.471

10.  YAP/TAZ Are Mechanoregulators of TGF-β-Smad Signaling and Renal Fibrogenesis.

Authors:  Stephen G Szeto; Masahiro Narimatsu; Mingliang Lu; Xiaolin He; Ahmad M Sidiqi; Monica F Tolosa; Lauren Chan; Krystale De Freitas; Janne Folke Bialik; Syamantak Majumder; Stellar Boo; Boris Hinz; Qinghong Dan; Andrew Advani; Rohan John; Jeffrey L Wrana; Andras Kapus; Darren A Yuen
Journal:  J Am Soc Nephrol       Date:  2016-03-09       Impact factor: 10.121

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