Literature DB >> 23125468

Surface Modification of Poly(amidoamine) (PAMAM) Dendrimer as Antimicrobial Agents.

Shakira Charles1, Nadarajah Vasanthan, Dong Kwon, Gabriela Sekosan, Subhas Ghosh.   

Abstract

Poly(amidoamine) (PAMAM) (G3) dendrimer was modified into quaternary ammonium salts using tertiary amines with different chain lengths: dimethyldodecyl amine, dimethylhexyl amine, and dimethylbutyl amine using an efficient synthetic route. The antimicrobial activity of these dendrimer ammonium salts against Staphylococcus and E-coli bacteria was examined using the disc diffusion method. It was found that quaternary ammonium salt prepared with the dimethyldodecyl amine exhibits antimicrobial efficacy against Staphalococus and E.coli bacteria.

Entities:  

Year:  2012        PMID： 23125468      PMCID： PMC3486433          DOI： 10.1016/j.tetlet.2012.09.098

Source DB:  PubMed          Journal:  Tetrahedron Lett        ISSN： 0040-4039            Impact factor:   2.415


  4 in total

1.  Terminal groups in Starburst dendrimers: activation and reactions with proteins.

Authors:  P Singh
Journal:  Bioconjug Chem       Date:  1998 Jan-Feb       Impact factor: 4.774

2.  Quaternary ammonium functionalized poly(propylene imine) dendrimers as effective antimicrobials: structure-activity studies.

Authors:  C Z Chen; N C Beck-Tan; P Dhurjati; T K van Dyk; R A LaRossa; S L Cooper
Journal:  Biomacromolecules       Date:  2000       Impact factor: 6.988

Review 3.  Functional polymers and dendrimers: reactivity, molecular architecture, and interfacial energy.

Authors:  J M Fréchet
Journal:  Science       Date:  1994-03-25       Impact factor: 47.728

Review 4.  The chemistry and applications of antimicrobial polymers: a state-of-the-art review.

Authors:  El-Refaie Kenawy; S D Worley; Roy Broughton
Journal:  Biomacromolecules       Date:  2007-04-11       Impact factor: 6.988
  4 in total
  6 in total

1.  Quaternary Ammonium Polyamidoamine Dendrimer Modified Quantum Dots as Fluorescent Probes for p-Fluorophenoxyacetic Acid Detection in Aqueous Solution.

Authors:  Xiao Xu; Yuan-Cheng Cao; Jun'An Liu; Yongjun Lin
Journal:  J Fluoresc       Date:  2017-09-11       Impact factor: 2.217

2.  Evaluation of cationic polyamidoamine dendrimers' dermal toxicity in the rat skin model.

Authors:  Katarzyna Winnicka; Magdalena Wroblewska; Katarzyna Sosnowska; Halina Car; Irena Kasacka
Journal:  Drug Des Devel Ther       Date:  2015-03-05       Impact factor: 4.162

Review 3.  Antimicrobial polymeric materials with quaternary ammonium and phosphonium salts.

Authors:  Yan Xue; Huining Xiao; Yi Zhang
Journal:  Int J Mol Sci       Date:  2015-02-06       Impact factor: 5.923

4.  In vitro antibacterial activity of poly (amidoamine)-G7 dendrimer.

Authors:  Mitra Gholami; Rashin Mohammadi; Mohsen Arzanlou; Fakhraddin Akbari Dourbash; Ebrahim Kouhsari; Gharib Majidi; Seyed Mohsen Mohseni; Shahram Nazari
Journal:  BMC Infect Dis       Date:  2017-06-05       Impact factor: 3.090

5.  Antibacterial activity of amino- and amido- terminated poly (amidoamine)-G6 dendrimer on isolated bacteria from clinical specimens and standard strains.

Authors:  Ayoob Rastegar; Shahram Nazari; Ahmad Allahabadi; Farahnaz Falanji; Fakhreddin Akbari Dourbash Akbari Dourbash; Zahra Rezai; Soudabeh Alizadeh Matboo; Reza Hekmat-Shoar; Seyed Mohsen Mohseni; Gharib Majidi
Journal:  Med J Islam Repub Iran       Date:  2017-09-24

6.  Retrovirus Drugs-Loaded PEGylated PAMAM for Prolonging Drug Release and Enhancing Efficiency in HIV Treatment.

Authors:  Thi Thinh Nguyen; Bao Phu Nguyen; Dinh Tien Dung Nguyen; Ngoc Hoi Nguyen; Dai Hai Nguyen; Cuu Khoa Nguyen
Journal:  Polymers (Basel)       Date:  2021-12-29       Impact factor: 4.329
  6 in total

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