Literature DB >> 23125292

The importance of cardiac MR in diagnosis of myocarditis in a 30-year-old man presenting with inferior ST elevation, elevated cardiac troponin but unobstructed coronary arteries.

Thomas Edward Pain1, Eva Sammut, Michael Sheaff, Saidi Mohiddin.   

Abstract

A 30-year-old man presented with chest pain, inferior ST elevation and elevated troponin T. Emergency coronary angiography showed unobstructed coronary arteries. A clinical diagnosis of myocarditis was made. This was supported by cardiac MRI (CMR) which showed a dilated left ventricle with severely impaired systolic function, and patchy delayed gadolinium enhancement (DGE). He was admitted to the coronary care unit where he had episodes of monomorphic ventricular tachycardia (VT). He was treated with ACE inhibitors, β-blockers and corticosteroids. Targeted cardiac biopsies were taken during admission, and also 6 weeks later; none showed histological evidence of myocarditis. Repeat CMR on day 11 showed improvement in left ventricular systolic function, extent of oedema and DGE. He has subsequently had episodes of nonsustained ventricular tachycardia and evidence of established myocardial scar on CMR several months later.

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Year:  2012        PMID: 23125292      PMCID: PMC4543066          DOI: 10.1136/bcr.03.2012.6093

Source DB:  PubMed          Journal:  BMJ Case Rep        ISSN: 1757-790X


  6 in total

1.  Guidelines for the diagnosis and treatment of non-ST-segment elevation acute coronary syndromes.

Authors:  Jean-Pierre Bassand; Christian W Hamm; Diego Ardissino; Eric Boersma; Andrzej Budaj; Francisco Fernández-Avilés; Keith A A Fox; David Hasdai; E Magnus Ohman; Lars Wallentin; William Wijns
Journal:  Eur Heart J       Date:  2007-06-14       Impact factor: 29.983

2.  Acute myocarditis presenting as acute coronary syndrome: role of early cardiac magnetic resonance in its diagnosis.

Authors:  Pierre A Monney; Neha Sekhri; Thomas Burchell; Charles Knight; Ceri Davies; Andrew Deaner; Michael Sheaf; Suhail Baithun; Steffen Petersen; Andrew Wragg; Ajay Jain; Mark Westwood; Peter Mills; Anthony Mathur; Saidi A Mohiddin
Journal:  Heart       Date:  2010-11-23       Impact factor: 5.994

3.  Evaluation of postmortem endomyocardial biopsy specimens from 38 patients with lymphocytic myocarditis: implications for role of sampling error.

Authors:  A J Hauck; D L Kearney; W D Edwards
Journal:  Mayo Clin Proc       Date:  1989-10       Impact factor: 7.616

4.  Cardiovascular magnetic resonance in myocarditis: A JACC White Paper.

Authors:  Matthias G Friedrich; Udo Sechtem; Jeanette Schulz-Menger; Godtfred Holmvang; Pauline Alakija; Leslie T Cooper; James A White; Hassan Abdel-Aty; Matthias Gutberlet; Sanjay Prasad; Anthony Aletras; Jean-Pierre Laissy; Ian Paterson; Neil G Filipchuk; Andreas Kumar; Matthias Pauschinger; Peter Liu
Journal:  J Am Coll Cardiol       Date:  2009-04-28       Impact factor: 24.094

Review 5.  Diagnosis and management of patients with acute cardiac symptoms, troponin elevation and culprit-free angiograms.

Authors:  Sean Gallagher; Dan A Jones; Vijay Anand; Saidi Mohiddin
Journal:  Heart       Date:  2012-05-11       Impact factor: 5.994

6.  Insensitivity of right ventricular endomyocardial biopsy in the diagnosis of myocarditis.

Authors:  L H Chow; S J Radio; T D Sears; B M McManus
Journal:  J Am Coll Cardiol       Date:  1989-10       Impact factor: 24.094

  6 in total

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