Literature DB >> 23124706

Therapeutic application of mesenchymal stem cells in bone and joint diseases.

Yi Liu1, Jianmei Wu, Youming Zhu, Jinxiang Han.   

Abstract

Mesenchymal stem cells (MSCs), the non-hematopoietic progenitor cells, are multi-potent stem cells from a variety of tissues with the capability of self-renewal, proliferation, differentiation into multi-lineage cell types, as well as anti-inflammatory and immunomodulatory. These properties make MSCs an ideal source of cell therapy in bone and joint diseases. This review describes the advances of animal study and preliminary clinical application in the past few years, related to MSC-based cell therapy in the common bone and joint diseases, including osteoarthritis, rheumatoid arthritis, osteoporosis, osteonecrosis of the femoral head and osteogenesis imperfecta. It highlights the promising prospect of MSC in clinical application of bone and joint diseases.

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Year:  2012        PMID: 23124706     DOI: 10.1007/s10238-012-0218-1

Source DB:  PubMed          Journal:  Clin Exp Med        ISSN: 1591-8890            Impact factor:   3.984


  128 in total

1.  [Treatment of early avascular necrosis of femoral head by core decompression combined with autologous bone marrow mesenchymal stem cells transplantation].

Authors:  Tingjie Chang; Kanglai Tang; Xu Tao; Honghui Cao; Hui Li; Qianbo Chen; Lei Chen; Jianbo Zhou; Binghua Zhou; Jianzhong Xu
Journal:  Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi       Date:  2010-06

2.  Avascular osteonecrosis of the femoral head treated with a vascularized iliac bone graft: preliminary results and follow-up with radiography and MR imaging.

Authors:  R P Wassenaar; H Verburg; W K Taconis; J W van der Eijken
Journal:  Radiographics       Date:  1996-05       Impact factor: 5.333

3.  Administering human adipose-derived mesenchymal stem cells to prevent and treat experimental arthritis.

Authors:  Bin Zhou; Jingdong Yuan; Yixuan Zhou; Maher Ghawji; Yun-Ping Deng; Austin J Lee; Albert J Lee; Usha Nair; Andrew H Kang; David D Brand; Tai June Yoo
Journal:  Clin Immunol       Date:  2011-09-02       Impact factor: 3.969

4.  [A study on repairing mandibular defect by means of tissue-engineering and human bone morphogenetic protein-2 gene transfection in osteoporotic rats].

Authors:  You-chao Tang; Wei Tang; Wei-dong Tian; Xi-zhe Chen; Sheng-wei Li
Journal:  Zhonghua Kou Qiang Yi Xue Za Zhi       Date:  2006-07

5.  Intra-bone marrow injection of mesenchymal stem cells improves the femur bone mass of osteoporotic female rats.

Authors:  Natália de Melo Ocarino; Jankerle Neves Boeloni; Vanda Jorgetti; Dawidson Assis Gomes; Alfredo Miranda Goes; Rogéria Serakides
Journal:  Connect Tissue Res       Date:  2010-04-07       Impact factor: 3.417

6.  Micro-CT-based bone ceramic scaffolding and its performance after seeding with mesenchymal stem cells for repair of load-bearing bone defect in canine femoral head.

Authors:  Jiang Peng; Cunyi Wen; Aiyuan Wang; Yu Wang; Wenjing Xu; Bin Zhao; Li Zhang; Shibi Lu; Ling Qin; Quanyi Guo; Limin Dong; Jiemo Tian
Journal:  J Biomed Mater Res B Appl Biomater       Date:  2011-02       Impact factor: 3.368

7.  Flk-1+ mesenchymal stem cells aggravate collagen-induced arthritis by up-regulating interleukin-6.

Authors:  B Chen; J Hu; L Liao; Z Sun; Q Han; Z Song; R C Zhao
Journal:  Clin Exp Immunol       Date:  2009-12-04       Impact factor: 4.330

8.  Injectable mesenchymal stem cell therapy for large cartilage defects--a porcine model.

Authors:  Kevin B L Lee; James H P Hui; Im Chim Song; Lenny Ardany; Eng Hin Lee
Journal:  Stem Cells       Date:  2007-07-26       Impact factor: 6.277

9.  Species variation in the mechanisms of mesenchymal stem cell-mediated immunosuppression.

Authors:  Guangwen Ren; Juanjuan Su; Liying Zhang; Xin Zhao; Weifang Ling; Andrew L'huillie; Jimin Zhang; Yongqing Lu; Arthur I Roberts; Weizhi Ji; Huatang Zhang; Arnold B Rabson; Yufang Shi
Journal:  Stem Cells       Date:  2009-08       Impact factor: 6.277

10.  Regeneration of human bones in hip osteonecrosis and human cartilage in knee osteoarthritis with autologous adipose-tissue-derived stem cells: a case series.

Authors:  Jaewoo Pak
Journal:  J Med Case Rep       Date:  2011-07-07
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  34 in total

Review 1.  Stem cell therapy for osteoporosis.

Authors:  Ben Antebi; Gadi Pelled; Dan Gazit
Journal:  Curr Osteoporos Rep       Date:  2014-03       Impact factor: 5.096

Review 2.  Osteogenic differentiation of amniotic fluid mesenchymal stromal cells and their bone regeneration potential.

Authors:  Caterina Pipino; Assunta Pandolfi
Journal:  World J Stem Cells       Date:  2015-05-26       Impact factor: 5.326

Review 3.  Clinical considerations of regenerative medicine in osteoporosis.

Authors:  Hiromu Ito
Journal:  Curr Osteoporos Rep       Date:  2014-06       Impact factor: 5.096

Review 4.  Toward regeneration of articular cartilage.

Authors:  Masahiro Iwamoto; Yoichi Ohta; Colleen Larmour; Motomi Enomoto-Iwamoto
Journal:  Birth Defects Res C Embryo Today       Date:  2013-09

5.  [Risedronate inhibits rat bone marrow adipogenesis and reduces RANKL expression in adipocytes].

Authors:  Jian Jin; Dadi Jin
Journal:  Nan Fang Yi Ke Da Xue Xue Bao       Date:  2019-08-30

6.  Neohesperidin promotes the osteogenic differentiation of human bone marrow stromal cells by inhibiting the histone modifications of lncRNA SNHG1.

Authors:  Chuanxin Zhang; Shuai Yuan; Yi Chen; Bo Wang
Journal:  Cell Cycle       Date:  2021-08-30       Impact factor: 5.173

7.  Knockdown of HDAC9 Inhibits Osteogenic Differentiation of Human Bone Marrow Mesenchymal Stem Cells Partially by Suppressing the MAPK Signaling Pathway.

Authors:  Bo Wang; Song Gong; Lizhi Han; Wenkai Shao; Zilin Li; Jiawei Xu; Xiao Lv; Baojun Xiao; Yong Feng
Journal:  Clin Interv Aging       Date:  2022-05-12       Impact factor: 3.829

8.  Direct conversion of human fibroblasts into functional osteoblasts by defined factors.

Authors:  Kenta Yamamoto; Tsunao Kishida; Yoshiki Sato; Keisuke Nishioka; Akika Ejima; Hiroyoshi Fujiwara; Toshikazu Kubo; Toshiro Yamamoto; Narisato Kanamura; Osam Mazda
Journal:  Proc Natl Acad Sci U S A       Date:  2015-04-27       Impact factor: 11.205

9.  Long non-coding RNA BDNF-AS modulates osteogenic differentiation of bone marrow-derived mesenchymal stem cells.

Authors:  Xiaobo Feng; Tao Lin; Xianzhe Liu; Cao Yang; Shuhua Yang; Dehao Fu
Journal:  Mol Cell Biochem       Date:  2017-12-15       Impact factor: 3.396

10.  Remission of collagen-induced arthritis through combination therapy of microfracture and transplantation of thermogel-encapsulated bone marrow mesenchymal stem cells.

Authors:  He Liu; Jianxun Ding; Jincheng Wang; Yinan Wang; Modi Yang; Yanbo Zhang; Fei Chang; Xuesi Chen
Journal:  PLoS One       Date:  2015-03-16       Impact factor: 3.240

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