Literature DB >> 23124073

The role of the IAP E3 ubiquitin ligases in regulating pattern-recognition receptor signalling.

Peter Vandenabeele1, Mathieu J M Bertrand.   

Abstract

An inflammatory response is initiated when innate immune pattern-recognition receptors (PRRs) expressed by different cell types detect constituents of invading microorganisms and endogenous intracellular molecules released by dying cells. The intracellular cascades activated by PRRs induce the expression and maturation of inflammatory molecules that coordinate the removal of the infectious agents and of the infected or damaged cells. In this Review, we discuss the findings implicating members of the inhibitor of apoptosis protein (IAP) family in the ubiquitylation-dependent regulation of PRR signalling. Understanding the role of IAPs in innate immunity may open new therapeutic perspectives for the treatment of PRR-dependent inflammatory diseases.

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Year:  2012        PMID： 23124073     DOI： 10.1038/nri3325

Source DB:  PubMed          Journal:  Nat Rev Immunol        ISSN： 1474-1733            Impact factor:   53.106


  109 in total

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2.  Cellular inhibitors of apoptosis are global regulators of NF-κB and MAPK activation by members of the TNF family of receptors.

Authors:  Eugene Varfolomeev; Tatiana Goncharov; Heather Maecker; Kerry Zobel; László G Kömüves; Kurt Deshayes; Domagoj Vucic
Journal:  Sci Signal       Date:  2012-03-20       Impact factor: 8.192

3.  A role for mitochondria in NLRP3 inflammasome activation.

Authors:  Rongbin Zhou; Amir S Yazdi; Philippe Menu; Jürg Tschopp
Journal:  Nature       Date:  2010-12-01       Impact factor: 49.962

4.  Drosophila immune deficiency (IMD) is a death domain protein that activates antibacterial defense and can promote apoptosis.

Authors:  P Georgel; S Naitza; C Kappler; D Ferrandon; D Zachary; C Swimmer; C Kopczynski; G Duyk; J M Reichhart; J A Hoffmann
Journal:  Dev Cell       Date:  2001-10       Impact factor: 12.270

5.  IAPs limit activation of RIP kinases by TNF receptor 1 during development.

Authors:  Maryline Moulin; Holly Anderton; Anne K Voss; Tim Thomas; Wendy Wei-Lynn Wong; Aleksandra Bankovacki; Rebecca Feltham; Diep Chau; Wendy D Cook; John Silke; David L Vaux
Journal:  EMBO J       Date:  2012-02-10       Impact factor: 11.598

6.  CARD-mediated autoinhibition of cIAP1's E3 ligase activity suppresses cell proliferation and migration.

Authors:  Juanita Lopez; Sidonie Wicky John; Tencho Tenev; Gilles J P Rautureau; Mark G Hinds; Floriana Francalanci; Rebecca Wilson; Meike Broemer; Massimo M Santoro; Catherine L Day; Pascal Meier
Journal:  Mol Cell       Date:  2011-05-05       Impact factor: 17.970

7.  Autocrine TNFalpha signaling renders human cancer cells susceptible to Smac-mimetic-induced apoptosis.

Authors:  Sean L Petersen; Lai Wang; Asligul Yalcin-Chin; Lin Li; Michael Peyton; John Minna; Patrick Harran; Xiaodong Wang
Journal:  Cancer Cell       Date:  2007-11       Impact factor: 31.743

8.  cIAP1/2 are direct E3 ligases conjugating diverse types of ubiquitin chains to receptor interacting proteins kinases 1 to 4 (RIP1-4).

Authors:  Mathieu J M Bertrand; Saskia Lippens; An Staes; Barbara Gilbert; Ria Roelandt; Jelle De Medts; Kris Gevaert; Wim Declercq; Peter Vandenabeele
Journal:  PLoS One       Date:  2011-09-12       Impact factor: 3.240

9.  A non-redundant role for Drosophila Mkk4 and hemipterous/Mkk7 in TAK1-mediated activation of JNK.

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Journal:  PLoS One       Date:  2009-11-03       Impact factor: 3.240

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Authors:  Theodore Tsichritzis; Peer C Gaentzsch; Stylianos Kosmidis; Anthony E Brown; Efthimios M Skoulakis; Petros Ligoxygakis; George Mosialos
Journal:  Development       Date:  2007-06-06       Impact factor: 6.868
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  36 in total

Review 1.  Understanding the regulation of pattern recognition receptors in inflammatory diseases - a 'Nod' in the right direction.

Authors:  Claire L Feerick; Declan P McKernan
Journal:  Immunology       Date:  2016-11-14       Impact factor: 7.397

Review 2.  Mechanisms regulating neutrophil survival and cell death.

Authors:  María Laura Gabelloni; Analía Silvina Trevani; Juan Sabatté; Jorge Geffner
Journal:  Semin Immunopathol       Date:  2013-02-01       Impact factor: 9.623

3.  CPNE1 silencing inhibits the proliferation, invasion and migration of human osteosarcoma cells.

Authors:  Zhenhuan Jiang; Jiannong Jiang; Bizeng Zhao; Huilin Yang; Yunliang Wang; Shang Guo; Youping Deng; Deyi Lu; Tieliang Ma; Hongwei Wang; Jinzhi Wang
Journal:  Oncol Rep       Date:  2017-12-04       Impact factor: 3.906

4.  IAPs protect host target tissues from graft-versus-host disease in mice.

Authors:  Tomomi Toubai; Corinne Rossi; Katherine Oravecz-Wilson; Chen Liu; Cynthia Zajac; Shin-Rong Julia Wu; Yaping Sun; Hideaki Fujiwara; Hiroya Tamaki; Daniel Peltier; Mary Riwes; Israel Henig; Stuart Brabbs; Colin S Duckett; Shaomeng Wang; Pavan Reddy
Journal:  Blood Adv       Date:  2017-08-16

5.  Changes in PUB22 Ubiquitination Modes Triggered by MITOGEN-ACTIVATED PROTEIN KINASE3 Dampen the Immune Response.

Authors:  Giulia Furlan; Hirofumi Nakagami; Lennart Eschen-Lippold; Xiyuan Jiang; Petra Majovsky; Kathrin Kowarschik; Wolfgang Hoehenwarter; Justin Lee; Marco Trujillo
Journal:  Plant Cell       Date:  2017-03-09       Impact factor: 11.277

6.  The E3 ubiquitin ligase XIAP restricts Anaplasma phagocytophilum colonization of Ixodes scapularis ticks.

Authors:  Maiara S Severo; Anthony Choy; Kimberly D Stephens; Olivia S Sakhon; Gang Chen; Duk-Won D Chung; Karine G Le Roch; Gregor Blaha; Joao H F Pedra
Journal:  J Infect Dis       Date:  2013-07-29       Impact factor: 5.226

7.  Pathogen-associated molecular patterns activate expression of genes involved in cell proliferation, immunity and detoxification in the amebocyte-producing organ of the snail Biomphalaria glabrata.

Authors:  Si-Ming Zhang; Eric S Loker; John T Sullivan
Journal:  Dev Comp Immunol       Date:  2015-11-22       Impact factor: 3.636

8.  Interferon gamma boosts the nucleotide oligomerization domain 2-mediated signaling pathway in human dendritic cells in an X-linked inhibitor of apoptosis protein and mammalian target of rapamycin-dependent manner.

Authors:  Tünde Fekete; Gabor Koncz; Brigitta Szabo; Andrea Gregus; Eva Rajnavölgyi
Journal:  Cell Mol Immunol       Date:  2015-11-02       Impact factor: 11.530

9.  Unique BIR domain sets determine inhibitor of apoptosis protein-driven cell death and NOD2 complex signal specificity.

Authors:  Steven M Chirieleison; Joseph K Rathkey; Derek W Abbott
Journal:  Sci Signal       Date:  2018-07-17       Impact factor: 8.192

10.  Shigella hijacks the glomulin-cIAPs-inflammasome axis to promote inflammation.

Authors:  Shiho Suzuki; Toshihiko Suzuki; Hitomi Mimuro; Tsunehiro Mizushima; Chihiro Sasakawa
Journal:  EMBO Rep       Date:  2017-11-30       Impact factor: 8.807
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