OBJECTIVE: Laryngeal cancer is one of the most common malignant neoplasms of the head and neck and occurs predominantly in males. Squamous cell carcinomas arising in the glottic region are the most common of all laryngeal cancers and more prevalent than the supraglottic ones. But this pattern is reverse in some countries. This study was done to investigate the epidemiologic aspect of this subject in Iran. STUDY DESIGN: Cross-sectional study SUBJECTS AND METHODS: During a ten-year period from 1997 to 2007, all patients referred to two tertiary referral hospitals with a diagnosis of laryngeal cancer were enrolled in this study. RESULTS: Laryngeal cancer was diagnosed in a total of 453 patients and confirmed histologically. The average patient age was 59.92 years. Men outnumbered women (9.5:1). Four hundred patients (88.5%) were tobacco smokers. The primary location of the tumor was supraglottic in 221 (49%) cases, followed by glottic in 163 (36.2%), transglottic (the tumor involved all regions of the larynx and the origin was unspecified) in 60 (13.3%), and subglottic in 7 (1.6%). CONCLUSION: In our series, although we excluded transglottic tumors, the supraglottic tumor was dominant and the ratio of supraglottic to glottic tumors was 1.36. This is compatible with results from countries with a reverse ratio.
OBJECTIVE:Laryngeal cancer is one of the most common malignant neoplasms of the head and neck and occurs predominantly in males. Squamous cell carcinomas arising in the glottic region are the most common of all laryngeal cancers and more prevalent than the supraglottic ones. But this pattern is reverse in some countries. This study was done to investigate the epidemiologic aspect of this subject in Iran. STUDY DESIGN: Cross-sectional study SUBJECTS AND METHODS: During a ten-year period from 1997 to 2007, all patients referred to two tertiary referral hospitals with a diagnosis of laryngeal cancer were enrolled in this study. RESULTS:Laryngeal cancer was diagnosed in a total of 453 patients and confirmed histologically. The average patient age was 59.92 years. Men outnumbered women (9.5:1). Four hundred patients (88.5%) were tobacco smokers. The primary location of the tumor was supraglottic in 221 (49%) cases, followed by glottic in 163 (36.2%), transglottic (the tumor involved all regions of the larynx and the origin was unspecified) in 60 (13.3%), and subglottic in 7 (1.6%). CONCLUSION: In our series, although we excluded transglottic tumors, the supraglottic tumor was dominant and the ratio of supraglottic to glottic tumors was 1.36. This is compatible with results from countries with a reverse ratio.
Authors: Y Shimizu; H Tsukagoshi; M Fujita; M Hosokawa; A Watanabe; S Kawabori; M Kato; T Sugiyama; M Asaka Journal: Endoscopy Date: 2003-04 Impact factor: 10.093
Authors: Eduardo De Stefani; Paolo Boffetta; Hugo Deneo-Pellegrini; Paul Brennan; Pelayo Correa; Fernando Oreggia; Alvaro L Ronco; María Mendilaharsu Journal: Int J Cancer Date: 2004-12-20 Impact factor: 7.396
Authors: Björn L D M Brücher; Yan Li; Philipp Schnabel; Martin Daumer; Timothy J Wallace; Rainer Kube; Bruno Zilberstein; Scott Steele; Jan L A Voskuil; Ijaz S Jamall Journal: Clin Transl Med Date: 2016-04-06