Literature DB >> 23120632

A comparative study of ceruminolytic agents.

Prashant Nair1, Sanjeev Golhar, Nitish Baisakhiya, P T Deshmukh.   

Abstract

A prospective study was done to access the efficacy of ceruminolytic agents, i.e 2% paradichlorobenzene, 10% sodium bicarbonate, 2.5% acetic acid and normal saline. All score 4 hard impacted ear wax cases in the adult population (>20 years) were accrued for the assessment of the relative efficacy. Upon analyzing the comparative efficacy of four ceruminolytic agents, by taking into consideration three parameters (post) ceruminolytic cerumen score, attempts of syringing required to extrude the cerumen mass, post-ceruminolytic use and appearance of the removed cerumen mass. 2% paradichlorobenzene emerged as the most superior ceruminolytic, closely followed by 10% sodium bicarbonate. 2.5% acetic acid fared moderately while normal saline emerged as the least efficacious ceruminolytic agent.

Entities:  

Keywords:  10% Sodium bicarbonate; 2% paradichlorobenzene; Acetic acid; Cerumen score; Ceruminolytic agents; Impacted wax

Year:  2009        PMID: 23120632      PMCID: PMC3449978          DOI: 10.1007/s12070-009-0063-z

Source DB:  PubMed          Journal:  Indian J Otolaryngol Head Neck Surg        ISSN: 2231-3796


  17 in total

1.  Micro-chemical studies on normal cerumen. I. The lipid and protein content of normal cerumen as affected by age and sex.

Authors:  S P CHIANG; O H LOWRY; B H SENTURIA
Journal:  Laryngoscope       Date:  1955-10       Impact factor: 3.325

2.  Invasive external otitis after removal of impacted cerumen by irrigation.

Authors:  D Zikk; Y Rapoport; M Z Himelfarb
Journal:  N Engl J Med       Date:  1991-09-26       Impact factor: 91.245

3.  An in-vitro comparison of the disintegration of human ear wax by five cerumenolytics commonly used in general practice.

Authors:  A K Mehta
Journal:  Br J Clin Pract       Date:  1985-05

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Authors:  M J Bellini; R M Terry; F A Lewis
Journal:  Clin Otolaryngol Allied Sci       Date:  1989-02

5.  The efficacy of wax solvents: in vitro studies and a clinical trial.

Authors:  J G Fraser
Journal:  J Laryngol Otol       Date:  1970-10       Impact factor: 1.469

6.  The efficacy of ceruminolytics: everything old is new again.

Authors:  A C Robinson; M Hawke
Journal:  J Otolaryngol       Date:  1989-10

7.  Age-related changes in sebaceous wax ester secretion rates in men and women.

Authors:  E Jacobsen; J K Billings; R A Frantz; C K Kinney; M E Stewart; D T Downing
Journal:  J Invest Dermatol       Date:  1985-11       Impact factor: 8.551

8.  A single-blind, randomized study to compare the efficacy of two ear drop preparations ('Audax' and 'Cerumol') in the softening of ear wax.

Authors:  D S Dummer; I A Sutherland; J A Murray
Journal:  Curr Med Res Opin       Date:  1992       Impact factor: 2.580

9.  A comparison of the efficacy of two ear drop preparations ('Audax' and 'Earex') in the softening and removal of impacted ear wax.

Authors:  S Lyndon; P Roy; M G Grillage; A J Miller
Journal:  Curr Med Res Opin       Date:  1992       Impact factor: 2.580

10.  Production rate and composition of cerumen: influence of sex and season.

Authors:  C Cipriani; G Taborelli; G Gaddia; A Melagrana; A Rebora
Journal:  Laryngoscope       Date:  1990-03       Impact factor: 3.325

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  1 in total

1.  Ceruminal diffusion activities and ceruminolytic characteristics of otic preparations - an in-vitro study.

Authors:  Jessica Stahl; Stefanie Mielke; Wolf-Rüdiger Pankow; Manfred Kietzmann
Journal:  BMC Vet Res       Date:  2013-04-10       Impact factor: 2.741

  1 in total

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