Literature DB >> 23119562

Recent advances in the molecular biology of head and neck tumours.

A K Bhattacharyya1, S Ghosh.   

Abstract

Our knowlcwdge about the genetic basis of head and neck tumours is accumulating fast. This article reviews the important advances in this area over the last decade and its implications for the future. Newer aspects of gene therapy, molecular staging and understanding head and neck carcinogenesis on a molecular level are outlined.

Entities:  

Keywords:  Head and Neck; Molecular Biology; Oncogenes; Squamous cell carcinoma; Tumour Suppressor Genes

Year:  1999        PMID： 23119562      PMCID： PMC3451383          DOI： 10.1007/BF03022707

Source DB:  PubMed          Journal:  Indian J Otolaryngol Head Neck Surg        ISSN： 2231-3796


  32 in total

1.  Integration of papillomavirus DNA near myc genes in genital carcinomas and its consequences for proto-oncogene expression.

Authors:  J Couturier; X Sastre-Garau; S Schneider-Maunoury; A Labib; G Orth
Journal:  J Virol       Date:  1991-08       Impact factor: 5.103

2.  The predictive value of p53, MDM-2, cyclin D1 and Ki67 in the progression from low-grade dysplasia towards carcinoma of the larynx.

Authors:  L Pignataro; P Capaccio; G Pruneri; N Carboni; R Buffa; A Neri; A Ottaviani
Journal:  J Laryngol Otol       Date:  1998-05       Impact factor: 1.469

3.  Role of nitric oxide in angiogenesis and tumor progression in head and neck cancer.

Authors:  O Gallo; E Masini; L Morbidelli; A Franchi; I Fini-Storchi; W A Vergari; M Ziche
Journal:  J Natl Cancer Inst       Date:  1998-04-15       Impact factor: 13.506

4.  Deletion and methylation of the tumour suppressor gene p16/CDKN2 in primary head and neck squamous cell carcinoma.

Authors:  M V González; M F Pello; C López-Larrea; C Suárez; M J Menéndez; E Coto
Journal:  J Clin Pathol       Date:  1997-06       Impact factor: 3.411

5.  Is p53 an independent prognostic factor in patients with laryngeal carcinoma?

Authors:  A Narayana; A T Vaughan; S Gunaratne; S Kathuria; S A Walter; S P Reddy
Journal:  Cancer       Date:  1998-01-15       Impact factor: 6.860

6.  Inactivation of p53 and amplification of cyclin D1 correlate with clinical outcome in head and neck cancer.

Authors:  C P Nogueira; R W Dolan; J Gooey; S Byahatti; C W Vaughan; N S Fuleihan; G Grillone; E Baker; G Domanowski
Journal:  Laryngoscope       Date:  1998-03       Impact factor: 3.325

7.  p53 protein expression in laryngeal squamous cell carcinomas bearing wild-type and mutated p53 gene.

Authors:  G Pruneri; L Pignataro; N S Fracchiolla; S Ferrero; P Capaccio; N Carboni; A Ottaviani; A T Maiolo; A Neri; R Buffa
Journal:  Histopathology       Date:  1996-06       Impact factor: 5.087

8.  High incidence of p53 alterations (mutation, deletion, overexpression) in head and neck primary tumors and metastases; absence of correlation with clinical outcome. Frequent protein overexpression in normal epithelium and in early non-invasive lesions.

Authors:  J C Ahomadegbe; M Barrois; S Fogel; M L Le Bihan; S Douc-Rasy; P Duvillard; J P Armand; G Riou
Journal:  Oncogene       Date:  1995-03-16       Impact factor: 9.867

Review 9.  Oncogenes and tumour-suppressor genes in squamous cell carcinoma of the head and neck.

Authors:  J K Field
Journal:  Eur J Cancer B Oral Oncol       Date:  1992-07

10.  Comparative genomic hybridization detects novel deletions and amplifications in head and neck squamous cell carcinomas.

Authors:  M R Speicher; C Howe; P Crotty; S du Manoir; J Costa; D C Ward
Journal:  Cancer Res       Date:  1995-03-01       Impact factor: 12.701
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