Literature DB >> 23119315

Itraconazole - a potent antifungal drug.

N K Panda1.   

Abstract

Itraconazole is an orally active triazole antifungal drug which has demonstrated a broad spectrum of activity and a favourable pharmacokinetic profile. It is a potent inhibitor of most human fungal pathogens including Aspergillus species.In non comparable clinical trials, Itraconazole was shown to be extremely effective in a wide range of superficial and more serious deep fungal infections when administered once or twice daily. Preliminary findings also indicate that itraconazole, may hold promise for the prophylaxis of opportunistic fungal infections in patients at risk, i.e. women with recurrent vaginal candidiasis, AIDS patients and patients receiving immunosuppressant drugs.

Entities:  

Year:  1997        PMID: 23119315      PMCID: PMC3450574          DOI: 10.1007/BF02991297

Source DB:  PubMed          Journal:  Indian J Otolaryngol Head Neck Surg        ISSN: 2231-3796


  3 in total

1.  Itraconazole suppresses the growth of glioblastoma through induction of autophagy: involvement of abnormal cholesterol trafficking.

Authors:  Rui Liu; Jingyi Li; Tao Zhang; Linzhi Zou; Yi Chen; Kui Wang; Yunlong Lei; Kefei Yuan; Yi Li; Jiang Lan; Lin Cheng; Na Xie; Rong Xiang; Edouard C Nice; Canhua Huang; Yuquan Wei
Journal:  Autophagy       Date:  2014-05-15       Impact factor: 16.016

2.  Evaluation of amphotericin B and chloramphenicol as alternative drugs for treatment of chytridiomycosis and their impacts on innate skin defenses.

Authors:  Whitney M Holden; Alexander R Ebert; Peter F Canning; Louise A Rollins-Smith
Journal:  Appl Environ Microbiol       Date:  2014-04-25       Impact factor: 4.792

3.  Antifungal efficacy of itraconazole-loaded TPGS-b-(PCL-ran-PGA) nanoparticles.

Authors:  Lixin Qiu; Bicheng Hu; Hongbo Chen; Shanshan Li; Yuqian Hu; Yi Zheng; Xinxing Wu
Journal:  Int J Nanomedicine       Date:  2015-02-17
  3 in total

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