Literature DB >> 23118663

Probable association of tachyarrhythmia with nebulized albuterol in a child with previously subclinical wolff Parkinson white syndrome.

Michiel Kroesen1, Machiel Maseland, Jaime Smal, Annet Reimer, Petra van Setten.   

Abstract

We present the case of a 2-year-old asthmatic boy with atrioventricular (AV)-reentry tachycardia following albuterol inhalation, who was later diagnosed with Wolff-Parkinson-White (WPW) syndrome. The Naranjo adverse drug reaction probability scale score for this adverse event was 7, indicating that the association between his AV-reentry tachycardia and inhalation of albuterol is probable. To our knowledge, this is the first case report that shows the potential arrhythmogenic effects of albuterol in a child with WPW syndrome. We urge clinicians to be aware of this potentially life-threatening adverse effect and to closely monitor these patients when they need beta-adrenergic drugs in case of emergency. Furthermore, this report highlights the dilemma regarding the safe treatment of pediatric patients with both asthma and WPW syndrome.

Entities:  

Keywords:  Wolff-Parkinson-White syndrome; adverse drug effect; albuterol; arrhythmias; asthma

Year:  2012        PMID: 23118663      PMCID: PMC3428194          DOI: 10.5863/1551-6776-17.1.93

Source DB:  PubMed          Journal:  J Pediatr Pharmacol Ther        ISSN: 1551-6776


  11 in total

1.  Electrocardiography in the patient with the Wolff-Parkinson-White syndrome: diagnostic and initial therapeutic issues.

Authors:  M H Rosner; W J Brady; M P Kefer; M L Martin
Journal:  Am J Emerg Med       Date:  1999-11       Impact factor: 2.469

Review 2.  The asthma epidemic.

Authors:  Waltraud Eder; Markus J Ege; Erika von Mutius
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3.  The safety and effects of the beta-blocker, nadolol, in mild asthma: an open-label pilot study.

Authors:  Nicola A Hanania; Supria Singh; Rami El-Wali; Michael Flashner; Amie E Franklin; William J Garner; Burton F Dickey; Sergio Parra; Stephen Ruoss; Felix Shardonofsky; Brian J O'Connor; Clive Page; Richard A Bond
Journal:  Pulm Pharmacol Ther       Date:  2007-07-17       Impact factor: 3.410

4.  Effects of isoproterenol on accessory pathway conduction in intermittent or concealed Wolff-Parkinson-White syndrome.

Authors:  T Yamamoto; S J Yeh; F C Lin; D L Wu
Journal:  Am J Cardiol       Date:  1990-06-15       Impact factor: 2.778

5.  A method for estimating the probability of adverse drug reactions.

Authors:  C A Naranjo; U Busto; E M Sellers; P Sandor; I Ruiz; E A Roberts; E Janecek; C Domecq; D J Greenblatt
Journal:  Clin Pharmacol Ther       Date:  1981-08       Impact factor: 6.875

6.  Prescribing of β-adrenoceptor antagonists in asthma: an observational study.

Authors:  Daniel R Morales; Bruce Guthrie; Brian J Lipworth; Peter T Donnan; Cathy Jackson
Journal:  Thorax       Date:  2011-04-01       Impact factor: 9.139

Review 7.  Optimizing maintenance therapy in pediatric asthma.

Authors:  Harold J Farber
Journal:  Curr Opin Pulm Med       Date:  2010-01       Impact factor: 3.155

8.  Evaluation of the asthmogenicity of propafenone, a new antiarrhythmic drug. Comparison of spirometry with methacholine challenge.

Authors:  M R Hill; V P Gotz; E Harman; I McLeod; L Hendeles
Journal:  Chest       Date:  1986-11       Impact factor: 9.410

9.  Repeated inhalation of nebulized albuterol did not induce arrhythmias in a patient with Wolff-Parkinson-White syndrome and asthma.

Authors:  A J Bonnin; G W Richmond; P K Musto; A S Volgman; J N Moy
Journal:  Chest       Date:  1993-06       Impact factor: 9.410

10.  Surgical therapy for Wolff-Parkinson-White syndrome in patients with bronchial asthma.

Authors:  H Ohtake; T Misaki; Y Matsunaga; M Tubota; M Kawasuji; Y Watanabe
Journal:  Cardiovasc Surg       Date:  1996-02
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  1 in total

1.  Assessment of atrial fibrillation and vulnerability in patients with Wolff-Parkinson-White syndrome using two-dimensional speckle tracking echocardiography.

Authors:  Jing-Jie Li; Fang Wei; Ju-Gang Chen; Yan-Wei Yu; Hong-Yue Gu; Rui Jiang; Xiu-Li Wu; Qian Sun
Journal:  PLoS One       Date:  2014-11-14       Impact factor: 3.240

  1 in total

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