| Literature DB >> 23118663 |
Michiel Kroesen1, Machiel Maseland, Jaime Smal, Annet Reimer, Petra van Setten.
Abstract
We present the case of a 2-year-old asthmatic boy with atrioventricular (AV)-reentry tachycardia following albuterol inhalation, who was later diagnosed with Wolff-Parkinson-White (WPW) syndrome. The Naranjo adverse drug reaction probability scale score for this adverse event was 7, indicating that the association between his AV-reentry tachycardia and inhalation of albuterol is probable. To our knowledge, this is the first case report that shows the potential arrhythmogenic effects of albuterol in a child with WPW syndrome. We urge clinicians to be aware of this potentially life-threatening adverse effect and to closely monitor these patients when they need beta-adrenergic drugs in case of emergency. Furthermore, this report highlights the dilemma regarding the safe treatment of pediatric patients with both asthma and WPW syndrome.Entities:
Keywords: Wolff-Parkinson-White syndrome; adverse drug effect; albuterol; arrhythmias; asthma
Year: 2012 PMID: 23118663 PMCID: PMC3428194 DOI: 10.5863/1551-6776-17.1.93
Source DB: PubMed Journal: J Pediatr Pharmacol Ther ISSN: 1551-6776