| Literature DB >> 23118418 |
Daniel Kolakofsky1, Eva Kowalinski, Stephen Cusack.
Abstract
A series of high-resolution crystal structures of RIG-I and RIG-I:dsRNA cocrystals has recently been reported. Comparison of these structures provides considerable insight into how this innate immune pattern recognition receptor is activated upon detecting and binding a certain class of viral RNAs.Entities:
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Year: 2012 PMID: 23118418 PMCID: PMC3504664 DOI: 10.1261/rna.035949.112
Source DB: PubMed Journal: RNA ISSN: 1355-8382 Impact factor: 4.942