Literature DB >> 23118269

Response to therapy following retreatment of serofast early syphilis patients with benzathine penicillin.

Arlene C Seña1, Mark Wolff, Frieda Behets, Kathleen Van Damme, David H Martin, Peter Leone, Linda McNeil, Edward W Hook.   

Abstract

Persistent nontreponemal titers after treatment are common among patients with early syphilis. We retreated 82 human immunodeficiency virus-negative early syphilis participants who were serofast at 6 months using benzathine penicillin. Only 27% exhibited serological response after retreatment and after an additional 6 months of follow-up.

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Year:  2012        PMID： 23118269      PMCID： PMC3590030          DOI： 10.1093/cid/cis918

Source DB:  PubMed          Journal:  Clin Infect Dis        ISSN： 1058-4838            Impact factor:   9.079


  5 in total

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Authors:  Kimberly A Workowski; Stuart Berman
Journal:  MMWR Recomm Rep       Date:  2010-12-17

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Authors:  Edward W Hook; Frieda Behets; Kathleen Van Damme; Noro Ravelomanana; Peter Leone; Arlene C Sena; David Martin; Carol Langley; Linda McNeil; Mark Wolff
Journal:  J Infect Dis       Date:  2010-06-01       Impact factor: 5.226

5.  Predictors of serological cure and Serofast State after treatment in HIV-negative persons with early syphilis.

Authors:  Arlene C Seña; Mark Wolff; David H Martin; Frieda Behets; Kathleen Van Damme; Peter Leone; Carol Langley; Linda McNeil; Edward W Hook
Journal:  Clin Infect Dis       Date:  2011-10-12       Impact factor: 9.079
  5 in total
  16 in total

1.  Sexually transmitted diseases treatment guidelines, 2015.

Authors:  Kimberly A Workowski; Gail A Bolan
Journal:  MMWR Recomm Rep       Date:  2015-06-05

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Authors:  Noah Kojima; Janet C Siebert; Holden Maecker; Yael Rosenberg-Hasson; Segundo R Leon; Silver K Vargas; Kelika A Konda; Carlos F Caceres; Jeffrey D Klausner
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Authors:  Craig Tipple; Rachael Jones; Myra McClure; Graham Taylor
Journal:  PLoS Negl Trop Dis       Date:  2015-02-20

6.  A systematic review of syphilis serological treatment outcomes in HIV-infected and HIV-uninfected persons: rethinking the significance of serological non-responsiveness and the serofast state after therapy.

Authors:  Arlene C Seña; Xiao-Hui Zhang; Trudy Li; He-Ping Zheng; Bin Yang; Li-Gang Yang; Juan C Salazar; Myron S Cohen; M Anthony Moody; Justin D Radolf; Joseph D Tucker
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Authors:  Li-Li Shao; Rui Guo; Wei-Jie Shi; Yuan-Jun Liu; Bin Feng; Long Han; Quan-Zhong Liu
Journal:  Medicine (Baltimore)       Date:  2016-12       Impact factor: 1.889

8.  Molecular subtyping of Treponema pallidum and associated factors of serofast status in early syphilis patients: Identified novel genotype and cytokine marker.

Authors:  Rui-Li Zhang; Qian-Qiu Wang; Jin-Ping Zhang; Li-Jia Yang
Journal:  PLoS One       Date:  2017-04-14       Impact factor: 3.240

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Authors:  Eric C Tang; Eddy R Segura; Jesse L Clark; Jorge Sanchez; Javier R Lama
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Review 10.  Emerging trends and persistent challenges in the management of adult syphilis.

Authors:  Susan Tuddenham; Khalil G Ghanem
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