Literature DB >> 23118121

Two-year follow-up study on clinical and radiological outcomes of polyurethane meniscal scaffolds.

Tineke De Coninck1, Wouter Huysse, Laurent Willemot, René Verdonk, Koenraad Verstraete, Peter Verdonk.   

Abstract

BACKGROUND: Little is known about radial displacement (RD) of polyurethane (PU) scaffolds, intended for partial meniscus defect substitution; no data are available on whether rim thickness influences RD and whether RD correlates with clinical outcome scores. HYPOTHESES: The meniscus is not extruded preoperatively, but RD occurs after scaffold implantation. A thicker rim will limit RD, and there is no correlation between RD and clinical outcome. STUDY
DESIGN: Case series; Level of evidence, 4.
METHODS: Twenty-six patients were implanted with a PU scaffold (8 lateral, 18 medial). Radial displacement (mm) was evaluated on magnetic resonance images preoperatively and at 3 months, 1 year, and 2 years postoperatively. At each time point, it was determined whether a correlation existed between the rim and RD. Clinical outcome was determined using a visual analog scale (VAS) for pain as well as the Lysholm knee scoring scale, Knee Injury and Osteoarthritis Outcome Score (KOOS), and International Knee Documentation Committee (IKDC) score.
RESULTS: Radial displacement of lateral scaffolds was not significantly different (P = .178) either preoperatively (mean ± SD, 3.42 ± 0.99 mm) or at 3 months (4.82 ± 0.59 mm), 1 year (4.55 ± 0.87 mm), or 2 years postoperatively (4.10 ± 0.93 mm). No correlation was observed between the rim and lateral RD at all time points. Medial scaffold RD increased significantly (P < .001) from preoperative values (2.17 ± 0.84 mm) to those at 3 months (4.25 ± 0.89 mm), 1 year (4.43 ± 1.01 mm), and 2 years postoperatively (4.41 ± 0.96 mm). A strong negative correlation between medial RD and the rim was observed at all time points. There was no significant correlation between clinical outcome scores and RD, either preoperatively or postoperatively.
CONCLUSION: This study demonstrated that limited medial meniscal RD was present preoperatively but increased by 2 mm after scaffold implantation. Lateral RD was also present preoperatively but did not increase after scaffold implantation. Importantly, a strong negative correlation was found between the rim and postoperative medial RD; a thicker rim limited RD. However, in the lateral compartment, rim thickness did not correlate with RD because RD was already strongly present preoperatively. Finally, no correlations were observed between scaffold RD and clinical outcome scores, either preoperatively or postoperatively.

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Year:  2012        PMID: 23118121     DOI: 10.1177/0363546512463344

Source DB:  PubMed          Journal:  Am J Sports Med        ISSN: 0363-5465            Impact factor:   6.202


  21 in total

1.  Polyurethane-based cell-free scaffold for the treatment of painful partial meniscus loss.

Authors:  G Filardo; E Kon; F Perdisa; A Sessa; A Di Martino; M Busacca; S Zaffagnini; M Marcacci
Journal:  Knee Surg Sports Traumatol Arthrosc       Date:  2016-07-09       Impact factor: 4.342

2.  Partial meniscus substitution with a polyurethane scaffold does not improve outcome after an open-wedge high tibial osteotomy.

Authors:  Pablo Eduardo Gelber; Anna Isart; Juan Ignacio Erquicia; Xavier Pelfort; Marc Tey-Pons; Juan Carlos Monllau
Journal:  Knee Surg Sports Traumatol Arthrosc       Date:  2014-07-29       Impact factor: 4.342

3.  What is the best way to fix a polyurethane meniscal scaffold? A biomechanical evaluation of different fixation modes.

Authors:  Francois Hardeman; Kristoff Corten; Michiel Mylle; Bert Van Herck; René Verdonk; Peter Verdonk; Johan Bellemans
Journal:  Knee Surg Sports Traumatol Arthrosc       Date:  2013-04-12       Impact factor: 4.342

4.  Midterm follow-up after implantation of a polyurethane meniscal scaffold for segmental medial meniscus loss: maintenance of good clinical and MRI outcome.

Authors:  Karl F Schüttler; Felix Haberhauer; Markus Gesslein; Thomas J Heyse; Jens Figiel; Olaf Lorbach; Turgay Efe; Philip P Roessler
Journal:  Knee Surg Sports Traumatol Arthrosc       Date:  2015-08-23       Impact factor: 4.342

5.  Cell distribution and regenerative activity following meniscus replacement.

Authors:  Cathal J Moran; Selma Atmaca; Heidi A Declercq; Maria J Cornelissen; Peter C Verdonk
Journal:  Int Orthop       Date:  2014-07-05       Impact factor: 3.075

6.  Updates in biological therapies for knee injuries: menisci.

Authors:  Camila Cohen Kaleka; Pedro Debieux; Diego da Costa Astur; Gustavo Gonçalves Arliani; Moisés Cohen
Journal:  Curr Rev Musculoskelet Med       Date:  2014-09

7.  Improvement in outcomes after implantation of a novel polyurethane meniscal scaffold for the treatment of medial meniscus deficiency.

Authors:  Karl F Schüttler; Steffen Pöttgen; Alan Getgood; Marga B Rominger; Susanne Fuchs-Winkelmann; Philip P Roessler; Ewgeni Ziring; Turgay Efe
Journal:  Knee Surg Sports Traumatol Arthrosc       Date:  2014-04-08       Impact factor: 4.342

8.  Polyurethane meniscal scaffolds lead to better clinical outcomes but worse articular cartilage status and greater absolute meniscal extrusion.

Authors:  Young-Soo Shin; Hoon-Nyun Lee; Hyun-Bo Sim; Hyun-Jung Kim; Dae-Hee Lee
Journal:  Knee Surg Sports Traumatol Arthrosc       Date:  2017-07-26       Impact factor: 4.342

9.  The Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) in Persian Speaking Patients with Knee Osteoarthritis.

Authors:  Mohammad H Ebrahimzadeh; Hadi Makhmalbaf; Ali Birjandinejad; Farideh Golhasani Keshtan; Hosein A Hoseini; Seyed Mahdi Mazloumi
Journal:  Arch Bone Jt Surg       Date:  2014-03-15

Review 10.  Meniscal scaffolds: results and indications. A systematic literature review.

Authors:  Giuseppe Filardo; Luca Andriolo; Elizaveta Kon; Francesca de Caro; Maurilio Marcacci
Journal:  Int Orthop       Date:  2014-06-29       Impact factor: 3.075

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