Literature DB >> 23117579

Synthesis and pharmacological activity of alkaloids from embryo of lotus, Nelumbo nucifera.

Katsumi Nishimura1, Shinji Horii, Takao Tanahashi, Yumi Sugimoto, Jun Yamada.   

Abstract

Bisbenzylisoquinoline alkaloid, nelumboferine which was recently isolated from the embryo of Nelumbo nucifera, and stereoisomers of neferine, which is a major alkaloid of the embryo of N. nucifera, were stereoselectively synthesized. Pharmacological activity of nelumboferine, stereoisomers of neferine, liensinine, isoliensinine, and O-methylneferine were evaluated.

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Year:  2012        PMID: 23117579     DOI: 10.1248/cpb.c12-00820

Source DB:  PubMed          Journal:  Chem Pharm Bull (Tokyo)        ISSN: 0009-2363            Impact factor:   1.645


  3 in total

Review 1.  Benzylisoquinoline Alkaloids Biosynthesis in Sacred Lotus.

Authors:  Ivette M Menéndez-Perdomo; Peter J Facchini
Journal:  Molecules       Date:  2018-11-06       Impact factor: 4.411

2.  Complete biosynthesis of the bisbenzylisoquinoline alkaloids guattegaumerine and berbamunine in yeast.

Authors:  James T Payne; Timothy R Valentic; Christina D Smolke
Journal:  Proc Natl Acad Sci U S A       Date:  2021-12-21       Impact factor: 12.779

Review 3.  Diversity in Chemical Structures and Biological Properties of Plant Alkaloids.

Authors:  Sweta Bhambhani; Kirtikumar R Kondhare; Ashok P Giri
Journal:  Molecules       Date:  2021-06-03       Impact factor: 4.411

  3 in total

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