| Literature DB >> 23116944 |
Jinhee Hyun1, Saravana Kanagavelu, Masayuki Fukata.
Abstract
Both anti-viral and anti-bacterial host defense mechanisms involve TRIF signaling. TRIF provides early clearance of pathogens and coordination of a local inflammatory ensemble through an interferon cascade, while it may trigger organ damage. The multipotentiality of TRIF-mediated immune machinery may direct the fate of our continuous battle with microbes.Entities:
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Year: 2012 PMID: 23116944 PMCID: PMC3537922 DOI: 10.1016/j.micinf.2012.10.011
Source DB: PubMed Journal: Microbes Infect ISSN: 1286-4579 Impact factor: 2.700