Literature DB >> 23116001

[Mechanism of weightlessness osteoporosis and preventive and therapeutic effect of traditional Chinese medicine].

Bin Zhu1, Hua Guo, Xi-Juan Hao, Qian Fu, Su-Min Hu.   

Abstract

Weightlessness environment can lead to the muscle atrophy and body fluid distribution upward,which can cause the bone calcium metabolism disorder and always accompanied by the loss of bone microstructure and increased rate of bone fracture. Under microgravity,the astronauts are much easier to decrease the Ca2+ ion in bone, which can cause serious osteoporosis. However the bone lost is not equilibrium, it is especially serious in the mechanism loading bone and the recovery process is more difficult. These are very different from the osteoporosis in older people and postmenopausal osteoporosis. It is necessary to find an optimal method to due with it. In traditional Chinese medicine theory,the kidney stores "Jing" and dominates the bone, thus a lot of bone related diseases can be treated through the kidney. A lot of clinical practices have also proved that the Chinese herbs used under the guidance of basic Chinese medicine theory are always good at the treatment of common osteoporosis. In simulated weightlessness experiment, people found that the kidney nourishment drugs do can prevent the decrease of BMD. So in this article we want to review the causes of weightlessness and the potentials applications of tradition Chinese medicine in the treatment of weightlessness osteoporosis.

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Year:  2012        PMID: 23116001

Source DB:  PubMed          Journal:  Zhongguo Gu Shang        ISSN: 1003-0034


  2 in total

1.  High-Throughput Sequencing Reveals CXCR4 and IGF1 Behave Different Roles in Weightlessness Osteoporosis.

Authors:  Dong Wang; Weihang Li; Ziyi Ding; Quan Shi; Shilei Zhang; Zhuoru Zhang; Zhibin Liu; Xiaocheng Wang; Ming Yan
Journal:  Stem Cells Int       Date:  2022-04-18       Impact factor: 5.131

2.  Simulated Microgravity Altered the Metabolism of Loureirin B and the Expression of Major Cytochrome P450 in Liver of Rats.

Authors:  Bo Chen; Jingjing Guo; Shibo Wang; Liting Kang; Yulin Deng; Yujuan Li
Journal:  Front Pharmacol       Date:  2018-10-12       Impact factor: 5.810

  2 in total

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