Cai Yuan-Kun1, Ye Tao. 1. Department of General Surgery, The Fifth People's Hospital of Shanghai Affiliated to Fudan University, Shanghai, China. yuankun@medmail.com.cn
Abstract
BACKGROUND/AIMS: Epidemiological studies indicate that relevance between appendix and colon cancer is controversial, but unfortunately, there is no data based on examination of immune indicator to reveal the relativity. METHODOLOGY: This study explored the relation-ship between appendix immunity and the right colon cancer by detecting the presence of NK cells in appendix tissues with immunohistochemistry. RESULTS: The number of NK cells in the appendix tissue was the highest in patients with appendix inflammation (37.2+1.1), while lowest in patients with colon cancer and normal appendix (30.9+1.7). CONCLUSIONS: The decrease of NK cells in the appendix tissue is correlated with the increased incidence of right colon cancer.
BACKGROUND/AIMS: Epidemiological studies indicate that relevance between appendix and colon cancer is controversial, but unfortunately, there is no data based on examination of immune indicator to reveal the relativity. METHODOLOGY: This study explored the relation-ship between appendix immunity and the right colon cancer by detecting the presence of NK cells in appendix tissues with immunohistochemistry. RESULTS: The number of NK cells in the appendix tissue was the highest in patients with appendix inflammation (37.2+1.1), while lowest in patients with colon cancer and normal appendix (30.9+1.7). CONCLUSIONS: The decrease of NK cells in the appendix tissue is correlated with the increased incidence of right colon cancer.