Literature DB >> 2311534

Development and properties of a cell culture produced vaccine for hog cholera based on the Chinese strain.

C Terpstra1, R Woortmeyer, S J Barteling.   

Abstract

The Chinese strain of hog cholera virus (HCV) was adapted to suspension cultures of the established swine kidney cell line SK6. The strain designated "Cedipest", is produced on the basis of a seedlot system. The masterseed virus was identified in vitro and in vivo, and was found free from extraneous pig pathogenic viruses by repeated animal inoculation followed by appropriate serological tests. A distinct and reproducible relationship was ascertained between infectivity in vitro and protection. Pigs inoculated with 400-600 TCID50 of the Cedipest strain proved fully protected against challenge with greater than 100 pig LD50 of a virulent strain of HCV at 7 days and at 6 month post vaccination.

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Year:  1990        PMID： 2311534

Source DB:  PubMed          Journal:  Dtsch Tierarztl Wochenschr        ISSN： 0341-6593


  16 in total

1.  Substitution of specific cysteine residues in the E1 glycoprotein of classical swine fever virus strain Brescia affects formation of E1-E2 heterodimers and alters virulence in swine.

Authors:  I Fernández-Sainz; L G Holinka; D Gladue; V O'Donnell; Z Lu; B K Gavrilov; G R Risatti; M V Borca
Journal:  J Virol       Date:  2011-05-11       Impact factor: 5.103

2.  Characterization of cytopathogenicity of classical swine fever virus isolate induced by Newcastle disease virus.

Authors:  S D Raut; K K Rajak; R Kumar; V K Singh; A Saxena; D Chaudhary; D Muthuchelvan; A B Pandey
Journal:  Virusdisease       Date:  2015-05-23

3.  Attenuated lapinized chinese strain of classical swine fever virus: complete nucleotide sequence and character of 3'-noncoding region.

Authors:  H X Wu; J F Wang; C Y Zhang; L Z Fu; Z S Pan; N Wang; P W Zhang; W G Zhao
Journal:  Virus Genes       Date:  2001       Impact factor: 2.332

4.  The E2 glycoprotein of classical swine fever virus is a virulence determinant in swine.

Authors:  G R Risatti; M V Borca; G F Kutish; Z Lu; L G Holinka; R A French; E R Tulman; D L Rock
Journal:  J Virol       Date:  2005-03       Impact factor: 5.103

5.  N-linked glycosylation status of classical swine fever virus strain Brescia E2 glycoprotein influences virulence in swine.

Authors:  G R Risatti; L G Holinka; I Fernandez Sainz; C Carrillo; Z Lu; M V Borca
Journal:  J Virol       Date:  2006-11-15       Impact factor: 5.103

6.  Classical swine fever virus p7 protein is a viroporin involved in virulence in swine.

Authors:  Douglas P Gladue; Lauren G Holinka; Eneko Largo; Ignacio Fernandez Sainz; Consuelo Carrillo; Vivian O'Donnell; Ryan Baker-Branstetter; Zhiqiang Lu; Xavier Ambroggio; Guillermo R Risatti; Jose L Nieva; Manuel V Borca
Journal:  J Virol       Date:  2012-04-11       Impact factor: 5.103

7.  Alteration of a Second Putative Fusion Peptide of Structural Glycoprotein E2 of Classical Swine Fever Virus Alters Virus Replication and Virulence in Swine.

Authors:  L G Holinka; E Largo; D P Gladue; V O'Donnell; G R Risatti; J L Nieva; M V Borca
Journal:  J Virol       Date:  2016-10-28       Impact factor: 5.103

8.  Mutations in classical swine fever virus NS4B affect virulence in swine.

Authors:  I Fernandez-Sainz; D P Gladue; L G Holinka; V O'Donnell; I Gudmundsdottir; M V Prarat; J R Patch; W T Golde; Z Lu; J Zhu; C Carrillo; G R Risatti; M V Borca
Journal:  J Virol       Date:  2009-11-18       Impact factor: 5.103

9.  Cellular immune response to hog cholera virus (HCV): T cells of immune pigs proliferate in vitro upon stimulation with live HCV, but the E1 envelope glycoprotein is not a major T-cell antigen.

Authors:  T G Kimman; A T Bianchi; G Wensvoort; T G de Bruin; C Meliefste
Journal:  J Virol       Date:  1993-05       Impact factor: 5.103

10.  Infectious RNA transcribed from an engineered full-length cDNA template of the genome of a pestivirus.

Authors:  R J Moormann; H G van Gennip; G K Miedema; M M Hulst; P A van Rijn
Journal:  J Virol       Date:  1996-02       Impact factor: 5.103
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