Literature DB >> 23114752

Interaction of platelets and anidulafungin against Aspergillus fumigatus.

Susanne Perkhofer1, Barbara Striessnig, Bettina Sartori, Barbara Hausott, Helmut W Ott, Cornelia Lass-Flörl.   

Abstract

The combination of platelets and anidulafungin at 0.03 μg/ml significantly (P < 0.05) reduced the germination rate and hyphal elongation in Aspergillus fumigatus compared to those with either anidulafungin only or an untreated control. Platelets decreased the expression of the fks gene, which plays an important role in cell wall synthesis. Our results suggest that human platelets plus anidulafungin might contribute to defense against A. fumigatus.

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Year:  2012        PMID： 23114752      PMCID： PMC3535898          DOI： 10.1128/AAC.01534-12

Source DB:  PubMed          Journal:  Antimicrob Agents Chemother        ISSN： 0066-4804            Impact factor:   5.191


  22 in total

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Journal:  Methods       Date:  2001-12       Impact factor: 3.608

2.  Collaboration of human phagocytes with LY 303366 for antifungal activity against Aspergillus fumigatus.

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Journal:  J Antimicrob Chemother       Date:  1999-04       Impact factor: 5.790

Review 3.  Echinocandin antifungal drugs.

Authors:  David W Denning
Journal:  Lancet       Date:  2003-10-04       Impact factor: 79.321

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Journal:  Clin Infect Dis       Date:  1997-11       Impact factor: 9.079

Review 5.  Invasive aspergillosis.

Authors:  D W Denning
Journal:  Clin Infect Dis       Date:  1998-04       Impact factor: 9.079

6.  Human platelets damage Aspergillus fumigatus hyphae and may supplement killing by neutrophils.

Authors:  L Christin; D R Wysong; T Meshulam; R Hastey; E R Simons; R D Diamond
Journal:  Infect Immun       Date:  1998-03       Impact factor: 3.441

Review 7.  Virulence factors of medically important fungi.

Authors:  L H Hogan; B S Klein; S M Levitz
Journal:  Clin Microbiol Rev       Date:  1996-10       Impact factor: 26.132

8.  Antimicrobial peptides from human platelets.

Authors:  Yi-Quan Tang; Michael R Yeaman; Michael E Selsted
Journal:  Infect Immun       Date:  2002-12       Impact factor: 3.441

9.  Platelets enhance activity of antimycotic substances against non-Aspergillus fumigatus Aspergillus species in vitro.

Authors:  Susanne Perkhofer; Krista Trappl; Barbara Striessnig; Walter Nussbaumer; Cornelia Lass-Flörl
Journal:  Med Mycol       Date:  2010-08-26       Impact factor: 4.076

10.  Combined action of micafungin, a new echinocandin, and human phagocytes for antifungal activity against Aspergillus fumigatus.

Authors:  Jung-Hyun Choi; Elmer Brummer; David A Stevens
Journal:  Microbes Infect       Date:  2004-04       Impact factor: 2.700
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  5 in total

1.  Differential gene expression in Aspergillus fumigatus induced by human platelets in vitro.

Authors:  Susanne Perkhofer; Christoph Zenzmaier; Emilie Frealle; Michael Blatzer; Hubert Hackl; Bettina Sartori; Cornelia Lass-Flörl
Journal:  Int J Med Microbiol       Date:  2015-01-17       Impact factor: 3.473

2.  Platelets are critical for survival and tissue integrity during murine pulmonary Aspergillus fumigatus infection.

Authors:  Benjamin Y Tischler; Nicholas L Tosini; Robert A Cramer; Tobias M Hohl
Journal:  PLoS Pathog       Date:  2020-05-14       Impact factor: 6.823

3.  Dysregulation of Key Proteinases in Aspergillus fumigatus Induced by Blood Platelets.

Authors:  Bahareh Arghavan; Mohammad Shafiee; Seyed Jamal Hashemi; Sadegh Khodavaisy; Nazanin Hosseinkhan; Mojtaba Didehdar; Muhammad Getso; Aliasghar Ayatollahi; Sassan Rezaie
Journal:  Rep Biochem Mol Biol       Date:  2021-04

Review 4.  Lethal thrombosis of the iliac artery caused by Aspergillus fumigatus after liver transplantation: case report and review of the literature.

Authors:  Jan-Paul Gundlach; Rainer Günther; Helmut Fickenscher; Marcus Both; Christoph Röcken; Thomas Becker; Felix Braun
Journal:  BMC Surg       Date:  2019-12-27       Impact factor: 2.102

5.  BTK Inhibitors Impair Platelet-Mediated Antifungal Activity.

Authors:  Vincenzo Nasillo; Ivana Lagreca; Daniela Vallerini; Patrizia Barozzi; Giovanni Riva; Monica Maccaferri; Ambra Paolini; Fabio Forghieri; Stefania Fiorcari; Rossana Maffei; Silvia Martinelli; Claudio Giacinto Atene; Ilaria Castelli; Roberto Marasca; Leonardo Potenza; Patrizia Comoli; Rossella Manfredini; Enrico Tagliafico; Tommaso Trenti; Mario Luppi
Journal:  Cells       Date:  2022-03-16       Impact factor: 6.600
  5 in total

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