Literature DB >> 2311426

Chitosan: evaluation of a new hemostatic agent.

G M Kind1, S D Bines, E D Staren, A J Templeton, S G Economou.   

Abstract

Topically applied chitosan fails to improve the control of bleeding in a liver laceration model when compared to pressure alone in both normal and heparinized rats, and both chitosan and pressure alone are significantly less effective in controlling bleeding than the application of thrombin. In addition, our histologic results suggest that there may be an increased inflammatory response by the healing liver following topical application of chitosan.

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Year:  1990        PMID: 2311426

Source DB:  PubMed          Journal:  Curr Surg        ISSN: 0149-7944


  5 in total

1.  Chitosan sponges to locally deliver amikacin and vancomycin: a pilot in vitro evaluation.

Authors:  Scott P Noel; Harry S Courtney; Joel D Bumgardner; Warren O Haggard
Journal:  Clin Orthop Relat Res       Date:  2010-08       Impact factor: 4.176

2.  Chitosan films: a potential local drug delivery system for antibiotics.

Authors:  Scott P Noel; Harry Courtney; Joel D Bumgardner; Warren O Haggard
Journal:  Clin Orthop Relat Res       Date:  2008-04-18       Impact factor: 4.176

Review 3.  The biology of distraction osteogenesis for correction of mandibular and craniomaxillofacial defects: A review.

Authors:  Subodh Shankar Natu; Iqbal Ali; Sarwar Alam; Kolli Yada Giri; Anshita Agarwal; Vrishali Ajit Kulkarni
Journal:  Dent Res J (Isfahan)       Date:  2014-01

4.  Haemostatic chitosan coated gauze: in vitro interaction with human blood and in-vivo effectiveness.

Authors:  M Pogorielov; O Kalinkevich; V Deineka; V Garbuzova; A Solodovnik; A Kalinkevich; T Kalinichenko; A Gapchenko; A Sklyar; S Danilchenko
Journal:  Biomater Res       Date:  2015-11-02

Review 5.  Chitosan-Based Composite Materials for Prospective Hemostatic Applications.

Authors:  Zhang Hu; Dong-Ying Zhang; Si-Tong Lu; Pu-Wang Li; Si-Dong Li
Journal:  Mar Drugs       Date:  2018-08-04       Impact factor: 5.118

  5 in total

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