Literature DB >> 23109494

Spontaneous formation of heterogeneous patches on polymer-lipid core-shell particle surfaces during self-assembly.

Carolina Salvador-Morales1, Pedro M Valencia, Weiwei Gao, Rohit Karnik, Omid C Farokhzad.   

Abstract

Spontaneous formation of heterogeneous patches on the surface of lipid-based nanoparticles (NPs) and microparticles (MPs) due to the segregation of two different functional groups. Patch formation is observed when tracing the functional groups with quantum dots, gold nanoparticles, and fluorescent dyes. This discovery could have important implications for the future design of self-assembled NPs and MPs for different biomedical applications.
Copyright © 2013 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

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Year:  2012        PMID： 23109494      PMCID： PMC4157734          DOI： 10.1002/smll.201201499

Source DB:  PubMed          Journal:  Small        ISSN： 1613-6810            Impact factor:   13.281


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