Literature DB >> 23108635

Ability to return to sports 5 years after matrix-associated autologous chondrocyte transplantation in an average population of active patients.

Lukas Zak1, Silke Aldrian, Barbara Wondrasch, Christian Albrecht, Stefan Marlovits.   

Abstract

BACKGROUND: Cartilage injuries often occur during sports activities, and return to sports after cartilage surgery is an important outcome parameter for different treatment methods in the competitive as well as the recreationally active population. HYPOTHESIS: At the time of midterm follow-up after matrix-associated autologous chondrocyte transplantation (MACT), return to recreational sports at the preinjury level will be possible. STUDY
DESIGN: Case series; Level of evidence, 4.
METHODS: Seventy patients (51 men, 19 women; age [mean ± standard deviation], 34.9 ± 8.6 y; range, 18-55 y) were clinically evaluated 5 years after MACT through subjective clinical scores such as the Knee Injury and Osteoarthritis Outcome Score (KOOS) sport and recreation subscales, the Tegner activity scale, and the Noyes sports activity rating scale. The level of sports participation was included in the investigation.
RESULTS: The results 5 years after MACT showed mean values of 60.1 for the KOOS-sport, 67.4 for the Noyes, and 3.8 for the Tegner scores, meaning that regular sports activity such as cycling or running on flat ground, as well as medium-level manual labor, is possible. We noted that 74.3% of our patients returned to at least their preinjury sports level.
CONCLUSION: Midterm postoperative results after MACT show that in a moderately active population, participation in regular sports is possible for most patients, at least at their preinjury recreational level and intensity, and there is a good rate of return to sports.

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Mesh:

Year:  2012        PMID: 23108635     DOI: 10.1177/0363546512462382

Source DB:  PubMed          Journal:  Am J Sports Med        ISSN: 0363-5465            Impact factor:   6.202


  10 in total

Review 1.  Return to sport after the surgical management of articular cartilage lesions in the knee: a meta-analysis.

Authors:  Aaron J Krych; Ayoosh Pareek; Alexander H King; Nick R Johnson; Michael J Stuart; Riley J Williams
Journal:  Knee Surg Sports Traumatol Arthrosc       Date:  2016-08-18       Impact factor: 4.342

Review 2.  Cartilage failures. Systematic literature review, critical survey analysis, and definition.

Authors:  Giuseppe Filardo; Luca Andriolo; Federica Balboni; Maurilio Marcacci; Elizaveta Kon
Journal:  Knee Surg Sports Traumatol Arthrosc       Date:  2014-09-06       Impact factor: 4.342

3.  Bone block augmentation from the iliac crest for treatment of deep osteochondral defects of the knee resembles biomechanical properties of the subchondral bone.

Authors:  S Grechenig; Michael Worlicek; R Penzkofer; F Zeman; R Kujat; P Heiss; G Pattappa; J Zellner; P Angele
Journal:  Knee Surg Sports Traumatol Arthrosc       Date:  2018-10-28       Impact factor: 4.342

4.  Accurate Reporting of Concomitant Procedures Is Highly Variable in Studies Investigating Knee Cartilage Restoration.

Authors:  William L Sheppard; Betina B Hinckel; Armin Arshi; Seth L Sherman; Kristofer J Jones
Journal:  Cartilage       Date:  2019-04-11       Impact factor: 4.634

5.  Bone marrow extract as a growth supplement for human iliac apophyseal chondrocyte culture.

Authors:  Balasubramanian Balakumar; Karthikeyan Rajagopal; Vrisha Madhuri
Journal:  Indian J Med Res       Date:  2016-12       Impact factor: 2.375

Review 6.  Matrix-Assisted Autologous Chondrocyte Transplantation in the Knee: A Systematic Review of Mid- to Long-Term Clinical Outcomes.

Authors:  Hayden B Schuette; Matthew J Kraeutler; Eric C McCarty
Journal:  Orthop J Sports Med       Date:  2017-06-06

7.  Third-Generation Autologous Chondrocyte Implantation at the Knee Joint Using the Igor Scaffold: A Case Series With 2-Year Follow-up.

Authors:  Lukas Zak; Anne Kleiner; Christian Albrecht; Brigitte Tichy; Silke Aldrian
Journal:  Orthop J Sports Med       Date:  2021-01-22

8.  Treatment of Knee Osteochondral Fractures.

Authors:  Mihai Alexandru Cordunianu; Iulian Antoniac; Marius Niculescu; Gheorghe Paltanea; Anca Daniela Raiciu; Horatiu Dura; Norin Forna; Ioana Dana Carstoc; Mihai Bogdan Cristea
Journal:  Healthcare (Basel)       Date:  2022-06-08

9.  POST-OPERATIVE SPORT PARTICIPATION AND SATISFACTION WITH RETURN TO ACTIVITY AFTER MATRIX-INDUCED AUTOLOGOUS CHONDROCYTE IMPLANTATION IN THE KNEE.

Authors:  Jay R Ebert; Gregory C Janes; David J Wood
Journal:  Int J Sports Phys Ther       Date:  2020-02

10.  Association Between Isokinetic Knee Strength and Perceived Function and Patient Satisfaction With Sports and Recreational Ability After Matrix-Induced Autologous Chondrocyte Implantation.

Authors:  Jay R Ebert; Anne Smith; Gregory C Janes; David J Wood
Journal:  Orthop J Sports Med       Date:  2019-12-19
  10 in total

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