Literature DB >> 23108625

Cytochrome P450 119 Compounds I Formed by Chemical Oxidation and Photooxidation Are the Same Species.

Zhi Su1, John H Horner1, Martin Newcomb1.   

Abstract

Compound I from cytochrome P450 119 prepared by the photooxidation method involving peroxynitrite oxidation of the resting enzyme to Compound II followed by photooxidation to Compound I was compared to Compound I generated by m-chloroperoxybenzoic acid (MCPBA) oxidation of the resting enzyme. The two methods gave the same UV/Visible spectra, the same products from oxidations of lauric acid and palmitic acid and their (ω-2,ω-2,ω-3,ω-3)-tetradeuterated analogues, and the same kinetics for oxidations of lauric acid and caprylic acid. The experimental identities between the transients produced by the two methods leave no doubt that the same Compound I species is formed by the two methods.
© 2019 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim.

Entities:  

Keywords:  Compound I; cytochromes; kinetics; oxidation; spectroscopy

Mesh：

Substances：

Year:  2012        PMID： 23108625      PMCID： PMC3930626          DOI： 10.1002/chem.201202254

Source DB:  PubMed          Journal:  Chemistry        ISSN： 0947-6539            Impact factor:   5.236


  19 in total

1.  Heme-Containing Oxygenases.

Authors:  Masanori Sono; Mark P. Roach; Eric D. Coulter; John H. Dawson
Journal:  Chem Rev       Date:  1996-11-07       Impact factor: 60.622

2.  Rate-controlling isomerizations in fatty acid oxidations by a cytochrome P450 compound I.

Authors:  Zhi Su; Xiaohong Chen; John H Horner; Martin Newcomb
Journal:  Chemistry       Date:  2012-02-01       Impact factor: 5.236

3.  Cytochrome P450: the active oxidant and its spectrum.

Authors:  Jonathan Rittle; Jarod M Younker; Michael T Green
Journal:  Inorg Chem       Date:  2010-04-19       Impact factor: 5.165

4.  Cytochrome P450 compound I: capture, characterization, and C-H bond activation kinetics.

Authors:  Jonathan Rittle; Michael T Green
Journal:  Science       Date:  2010-11-12       Impact factor: 47.728

Review 5.  Spectroscopic characterization of cytochrome P450 Compound I.

Authors:  Christiane Jung; Simon de Vries; Volker Schünemann
Journal:  Arch Biochem Biophys       Date:  2010-12-30       Impact factor: 4.013

6.  Reaction of cytochrome P450BM3 and peroxynitrite yields nitrosyl complex.

Authors:  Rachel K Behan; Lee M Hoffart; Kari L Stone; Carsten Krebs; Michael T Green
Journal:  J Am Chem Soc       Date:  2007-04-14       Impact factor: 15.419

7.  Synthesis of Peroxynitrite in a Two-Phase System Using Isoamyl Nitrite and Hydrogen Peroxide

Authors: 
Journal:  Anal Biochem       Date:  1996-05-01       Impact factor: 3.365

Review 8.  Hydrocarbon hydroxylation by cytochrome P450 enzymes.

Authors:  Paul R Ortiz de Montellano
Journal:  Chem Rev       Date:  2010-02-10       Impact factor: 60.622

9.  Kinetics and activation parameters for oxidations of styrene by Compounds I from the cytochrome P450(BM-3) (CYP102A1) heme domain and from CYP119.

Authors:  Xinting Yuan; Qin Wang; John H Horner; Xin Sheng; Martin Newcomb
Journal:  Biochemistry       Date:  2009-09-29       Impact factor: 3.162

10.  Quantitative production of compound I from a cytochrome P450 enzyme at low temperatures. Kinetics, activation parameters, and kinetic isotope effects for oxidation of benzyl alcohol.

Authors:  Qin Wang; Xin Sheng; John H Horner; Martin Newcomb
Journal:  J Am Chem Soc       Date:  2009-08-05       Impact factor: 15.419
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  2 in total

Review 1.  Reactive intermediates in cytochrome p450 catalysis.

Authors:  Courtney M Krest; Elizabeth L Onderko; Timothy H Yosca; Julio C Calixto; Richard F Karp; Jovan Livada; Jonathan Rittle; Michael T Green
Journal:  J Biol Chem       Date:  2013-04-30       Impact factor: 5.157

2.  Reaction Intermediates and Molecular Mechanism of Peroxynitrite Activation by NO Synthases.

Authors:  Jérôme Lang; Amandine Maréchal; Manon Couture; Jérôme Santolini
Journal:  Biophys J       Date:  2016-11-15       Impact factor: 4.033
  2 in total

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