Literature DB >> 23106672

Quality of life of parents living with a child suffering from atopic dermatitis before and after a 3-month treatment with an emollient.

Carlo Gelmetti1, Franck Boralevi, Sophie Seité, Ramon Grimalt, Philippe Humbert, Thomas Luger, Jean-Francois Stalder, Alain Taïeb, Dominique Tennstedt, Rita Garcia Diaz, André Rougier.   

Abstract

Atopic dermatitis (AD) can be extremely disabling and may cause psychological problems for affected children and their families. Moisturizers and emollients are important in the baseline daily skin care of patients with AD. To assess the effect of a 3-month, twice-daily treatment with an emollient on the quality of life (QoL) of parents with a child with mild to moderate AD (SCORing Atopic Dermatitis [SCORAD] ≤ 30, a multicenter open trial was performed by eight dermatologists on 191 volunteers. Evaluation by the dermatologist of the child's clinical condition (SCORAD) and of the efficacy and overall safety of the treatment was associated with a QoL questionnaire completed by one parent of the atopic child. A self-assessment of the global QoL and of the efficacy and overall safety was also performed. During the study, mean SCORAD dropped from 28 to 12 (p < 0.001), with good improvement in skin dryness and pruritus criteria. At the same time, the self-assessment of the global parent QoL scores dropped from 4.4 to 2.1 (p < 0.001) with 60%, 48% and 79% favorable parent opinions regarding wellbeing or improvement of the health condition, quality of sleep, and efficacy of the emollient, respectively. This trial revealed the efficacy of the product in improving parent QoL (85% of parents noted improvement in QoL), and its global safety was considered to be very good or good, with 80% favorable opinions in parents' declarative judgements and dermatologists' assessments. The emollient evaluated improves the course of AD and can improve the QoL of patients and their families.
© 2012 Wiley Periodicals, Inc.

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Year:  2012        PMID: 23106672     DOI: 10.1111/j.1525-1470.2012.01817.x

Source DB:  PubMed          Journal:  Pediatr Dermatol        ISSN: 0736-8046            Impact factor:   1.588


  6 in total

Review 1.  Non-pharmacologic therapies for atopic dermatitis.

Authors:  Peter A Lio
Journal:  Curr Allergy Asthma Rep       Date:  2013-10       Impact factor: 4.806

2.  Local rhamnosoft, ceramides and L-isoleucine in atopic eczema: a randomized, placebo controlled trial.

Authors:  Alessia Marseglia; Amelia Licari; Fabio Agostinis; Antonio Barcella; Domenico Bonamonte; Mario Puviani; Massimo Milani; GianLuigi Marseglia
Journal:  Pediatr Allergy Immunol       Date:  2014-05       Impact factor: 6.377

3.  BATHING, MAKE-UP, AND SUNSCREEN: WHICH PRODUCTS DO CHILDREN USE?

Authors:  Thayane Guimarães de Melo; Mayara Schulze Cosechen Rosvailer; Vânia Oliveira de Carvalho
Journal:  Rev Paul Pediatr       Date:  2020-05-08

Review 4.  A Systematic Scoping Literature Review of Publications Supporting Treatment Guidelines for Pediatric Atopic Dermatitis in Contrast to Clinical Practice Patterns.

Authors:  Elaine C Siegfried; Jennifer C Jaworski; Paola Mina-Osorio
Journal:  Dermatol Ther (Heidelb)       Date:  2018-06-01

Review 5.  Alternative, Complementary, and Forgotten Remedies for Atopic Dermatitis.

Authors:  Allison L Goddard; Peter A Lio
Journal:  Evid Based Complement Alternat Med       Date:  2015-07-15       Impact factor: 2.629

6.  Piperine Ameliorates Trimellitic Anhydride-Induced Atopic Dermatitis-Like Symptoms by Suppressing Th2-Mediated Immune Responses via Inhibition of STAT6 Phosphorylation.

Authors:  Dae Woon Choi; Sun Young Jung; Dong-Hwa Shon; Hee Soon Shin
Journal:  Molecules       Date:  2020-05-07       Impact factor: 4.411

  6 in total

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